Evidence map›Paper›PMID 38476931›Full record

ArticleNeuro-oncology advances

Unraveling the relations between post-traumatic stress symptoms, neurocognitive functioning, and limbic white matter in pediatric brain tumor patients.

Anne E M Leenders, Eva Kremer-Hooft van Huijsduijnen, Bruno Robalo, Rosa van Male, Alberto De Luca, Rachèl Kemps, Eelco Hoving, Maarten H Lequin, Martha A Grootenhuis, Marita Partanen

Open access · goldAbstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Anne E M LeendersPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-9737-6535
Eva Kremer-Hooft van HuijsduijnenPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-8519-4785
Bruno RobaloPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-9957-5039
Rosa van MalePrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Alberto De LucaUniversity Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-2553-7299
Rachèl KempsPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-7217-0995
Eelco HovingPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-5587-0439
Maarten H LequinPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-7488-1734
Martha A GrootenhuisPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-9632-248X
Marita PartanenPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-1018-9778
Princess Máxima Center · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric brain tumor patients are at risk of developing neurocognitive impairments and associated white matter alterations. In other populations, post-traumatic stress symptoms (PTSS) impact cognition and white matter. This study aims to investigate the effect of PTSS on neurocognitive functioning and limbic white matter in pediatric brain tumor patients. Methods: Sixty-six patients (6-16 years) completed neuropsychological assessment and brain MRI (1-year post-diagnosis) and parents completed PTSS proxy questionnaires (CRIES-13; 1-3 months and 1-year post-diagnosis). Mean Results: Attention ( Conclusions: Higher PTSS was associated with poorer processing speed, highlighting the need for monitoring, and timely referrals to optimize psychological well-being and neurocognitive functioning. Future research should focus on longitudinal follow-up and explore the impact of PTSS interventions on neurocognitive performance.

Indexed as

limbic systemneurocognitionpediatric brain tumorPTSSwhite matter

Identifiers

PMID38476931
PMCPMC10929421
OpenAlexW4392780803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.