Evidence map›Paper›PMID 38476873›Full record

ReviewJournal of pain research2024

Expert Consensus on Ion Channel Drugs for Chronic Pain Treatment in China.

Ke Ma, Zhixiang Cheng, Hao Jiang, Zhangya Lin, Chuansheng Liu, Xianguo Liu, Lijuan Lu, Yan Lu, Wei Tao, Suoliang Wang and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of pain research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Personalizing treatment of pancreatitis-associated chronic pain: the need for an integrated omics approach.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 14 institutions in 1 country.

Ke Ma *Department of Algology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Zhixiang Cheng *Department of Algology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Hao Jiang *Department of Algology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.
Zhangya Lin *Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.
Chuansheng Liu *Department of Algology, The Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China.
Xianguo Liu *Pain Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, People's Republic of China.ORCID 0000-0002-4352-8687
Lijuan Lu *Department of Pain Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, People's Republic of China.
Yan Lu *Department of Algology, Xijing Hospital, The Fourth Military Medical University, Xian, People's Republic of China.ORCID 0000-0002-2868-2352
Wei Tao *Department of Neurosurgery, Shenzhen University General Hospital, Shenzhen, People's Republic of China.
Suoliang Wang *Department of Algology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Xiaoqiu Yang *Department of Algology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Qishan Yi *Department of Algology, The Yibin First People's Hospital Affiliated Chongqing Medical University, Yibin, People's Republic of China.
Xiaomei Zhang *Department of Algology, The First Affiliated Hospital of Kunming Medical University, Kunming, People's Republic of China.
Ying Zhang *Department of Algology. Hospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, People's Republic of China.
Yanqing Liu *Department of Algology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Fujian Medical University · CNCapital Medical University · CNChongqing Medical University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNKunming Medical University · CNNanjing Drum Tower Hospital · CNQingdao University · CNSecond Affiliated Hospital of Nanjing Medical University · CNShanghai Jiao Tong University · CNShenzhen University · CNSouthwest Medical University · CNSun Yat-sen University · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ion channel drugs have been increasing used for chronic pain management with progress in the development of selective calcium channel modulators. Although ion channel drugs have been proven safe and effective in clinical practice, uncertainty remains regarding its use to treat chronic pain. To standardize the clinical practice of ion channel drug for the treatment of chronic pain, the National Health Commission Capacity Building and Continuing Education Center for Pain Diagnosis and Treatment Special Ability Training Project established an expert group to form an expert consensus on the use of ion channel drugs for the treatment of chronic pain after repeated discussions on existing medical evidence combined with the well clinical experience of experts. The consensus provided information on the mechanism of action of ion channel drugs and their recommendations, caution use, contraindications, and precautions for their use in special populations to support doctors in their clinical decision-making.

Indexed as

chronic painion channel drugsvoltage-gated calcium channelsvoltage-gated sodium channel

Identifiers

PMID38476873
PMCPMC10929561
OpenAlexW4392590561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.