Evidence map›Paper›PMID 38476277›Full record

ArticleInternational journal of nanomedicine2024

Bare-Metal Stent Tracking with Magnetic Particle Imaging.

Franz Wegner, Thomas Friedrich, Maximilian Wattenberg, Justin Ackers, Malte Maria Sieren, Roman Kloeckner, Joerg Barkhausen, Thorsten M Buzug, Matthias Graeser, Anselm von Gladiss

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Franz WegnerInstitute for Interventional Radiology, University of Luebeck, Luebeck, Germany.ORCID 0000-0001-5969-3428
Thomas FriedrichFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Luebeck, Germany.
Maximilian WattenbergFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Luebeck, Germany.
Justin AckersFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Luebeck, Germany.
Malte Maria SierenInstitute for Interventional Radiology, University of Luebeck, Luebeck, Germany.ORCID 0000-0002-3669-2892
Roman KloecknerInstitute for Interventional Radiology, University of Luebeck, Luebeck, Germany.ORCID 0000-0001-5492-4792
Joerg BarkhausenDepartment of Radiology and Nuclear Medicine, University of Luebeck, Luebeck, Germany.ORCID 0000-0001-8937-1198
Thorsten M BuzugFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Luebeck, Germany.
Matthias GraeserFraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE, Luebeck, Germany.
Anselm von GladissInstitute for Computer Science, University of Koblenz, Koblenz, Germany.ORCID 0000-0003-1340-4576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Magnetic particle imaging (MPI) is an emerging medical imaging modality that is on the verge of clinical use. In recent years, cardiovascular applications have shown huge potential like, e.g., intraprocedural imaging guidance of stent placement through MPI. Due to the lack of signal generation, nano-modifications have been necessary to visualize commercial medical instruments until now. In this work, it is investigated if commercial interventional devices can be tracked with MPI without any nano-modification. Material and Methods: Potential MPI signal generation of nine endovascular metal stents was tested in a commercial MPI scanner. Two of the stents revealed sufficient MPI signal. Because one of the two stents showed relevant heating, the imaging experiments were carried out with a single stent model (Boston Scientific/Wallstent-Uni Endoprothesis, diameter: 16 mm, length: 60 mm). The nitinol stent and its delivery system were investigated in seven different scenarios. Therefore, the samples were placed at 49 defined spatial positions by a robot in a meandering pattern during MPI scans. Image reconstruction was performed, and the mean absolute errors (MAE) between the signals' centers of mass (COM) and ground truth positions were calculated. The stent material was investigated by magnetic particle spectroscopy (MPS) and vibrating sample magnetometry (VSM). To detect metallic components within the delivery system, nondestructive testing via computed tomography was performed. Results: The tracking of the stent and its delivery system was possible without any nano-modification. The MAE of the COM were 1.49 mm for the stent mounted on the delivery system, 3.70 mm for the expanded stent and 1.46 mm for the delivery system without the stent. The results of the MPS and VSM measurements indicate that besides material properties eddy currents seem to be responsible for signal generation. Conclusion: It is possible to image medical instruments with dedicated designs without modifications by means of MPI. This enables a variety of applications without compromising the mechanical and biocompatible properties of the instruments.

Indexed as

StentsTomography, X-Ray ComputedImage Processing, Computer-AssistedMagnetic PhenomenaMagneticsinstrument trackinginterventional instrumentsmagnetic particle imagingmedical imagingstent

Identifiers

PMID38476277
PMCPMC10929257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.