Evidence map›Paper›PMID 38476191›Full record

ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2022

Resolution Limit in Infrared Chemical Imaging.

Yamuna Phal, Luke Pfister, P Scott Carney, Rohit Bhargava

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
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  8. Article
  9. Digital Histopathology by Infrared Spectroscopic Imaging.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yamuna PhalDepartment of Electrical and Computer Engineering, University of Illinois at Urbana - Champaign, Urbana, Illinois 61801, United States; Beckman Institute for Advanced Science and Technology, Urbana, Illinois 61801, United States.
Luke PfisterDynamic Imaging & Radiography Group, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, United States.
P Scott CarneyInstitute of Optics, University of Rochester, Rochester, New York 14627, United States.
Rohit BhargavaDepartment of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States; Beckman Institute for Advanced Science and Technology, Urbana, Illinois 61801, United States; Departments of Bioengineering, Chemical and Biomolecular Engineering, Mechanical Science and Engineering, and Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States; Cancer Center at Illinois, Beckman Institute for Advanced Science and Technology, Urbana, Illinois 61801, United States.ORCID 0000-0001-7360-994X
University of Illinois Urbana-Champaign · USLos Alamos National Laboratory · USUniversity of Rochester · US

Funding

Discrete Frequency Infrared Spectroscopic Imaging for Breast HistopathologyR01EB009745 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT · 2010 to 2025
$5.1M
Real time colon histopathology by infrared spectroscopic imagingR01CA260830 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT · 2021 to 2025
$2.3M
Instrument development for vibrational circular dichroism imagingR01GM142172 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT · 2021 to 2024
$1.6M
NCI NIH HHS R01 CA260830NIBIB NIH HHS R01 EB009745NIGMS NIH HHS R01 GM142172
6 · The paper itself

Abstract

Chemical imaging combines the spatial specificity of optical microscopy with the spectral selectivity of vibrational spectroscopy. Mid-infrared (IR) absorption imaging instruments are now able to capture high-quality spectra with microscopic spatial detail, but the limits of their ability to resolve spatial and spectral objects remain less understood. In particular, the sensitivity of measurements to chemical and spatial changes and rules for optical design have been presented, but the influence of spectral information on spatial sensitivity is as yet relatively unexplored. We report an information theory-based approach to quantify the spatial localization capability of spectral data in chemical imaging. We explicitly consider the joint effects of the signal-to-noise ratio and spectral separation that have significance in experimental settings to derive resolution limits in IR spectroscopic imaging.

Identifiers

PMID38476191
PMCPMC10928383
OpenAlexW4293069867

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.