Evidence map›Paper›PMID 38476179›Full record

ArticleRSC advances2024

Hetastarch-stabilized polypyrrole with hyperthermia-enhanced release and catalytic activity for synergistic antitumor therapy.

Xiaoyun Huang, Zhiming Liu, Weijian Zeng, Xiaoyu Ma, Yu Zhang, Muye Li, Jiutong Sun, Sheng Mao, Li Bian

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xiaoyun HuangSchool of Clinical Medicine, Qujing Medical College Qujing 655100 Yunnan China hhuo0010@163.com.
Zhiming LiuDepartment of Urinary, Qujing No. 1 Hospital Qujing 655000 Yunnan China.
Weijian ZengCollege of Science and Technology, Ningbo University Ningbo 315300 Zhejiang China.
Xiaoyu MaSchool of Clinical Medicine, Qujing Medical College Qujing 655100 Yunnan China hhuo0010@163.com.
Yu ZhangDepartment of Pathology, The First Affiliated Hospital of Kunming Medical University Kunming 650032 Yunnan China bianli1976@sina.com.
Muye LiDepartment of Pathology, The First Affiliated Hospital of Kunming Medical University Kunming 650032 Yunnan China bianli1976@sina.com.
Jiutong SunCollege of Science and Technology, Ningbo University Ningbo 315300 Zhejiang China.
Sheng MaoSchool of Clinical Medicine, Qujing Medical College Qujing 655100 Yunnan China hhuo0010@163.com.
Li BianDepartment of Pathology, The First Affiliated Hospital of Kunming Medical University Kunming 650032 Yunnan China bianli1976@sina.com.
Kunming Medical University · CNQujing Normal University · CNNingbo University · CNFirst Affiliated Hospital of Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fenton catalytic medicine that catalyzes the production of ·OH without external energy input or oxygen as a substrate has reshaped the landscape of conventional cancer therapy in recent decades, yet potential biosafety concerns caused by non-safety-approved components restrict their clinical translation from the bench to the bedside. Herein, to overcome this dilemma, we elaborately utilizate safety-approved hetastarch, which has been extensively employed in the clinic as a plasma substitute, as a stabilizer participating in the copper chloride-initiated polymerization of pyrrole monomer before loading it with DOX. The constructed DOX-loaded hetastarch-doped Cu-based polypyrrole (HES@CuP-D) catalyzes the excess H

Identifiers

PMID38476179
PMCPMC10929590
OpenAlexW4392719176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.