Evidence map›Paper›PMID 38476150›Full record

ArticleGE Portuguese journal of gastroenterology2023

The New FibroScan-AST (FAST) Score: Enhancing Diabetes Mellitus Impact on Metabolic-Associated Fatty Liver Disease.

Vítor Macedo Silva, Marta Freitas, Sofia Xavier, Pedro Boal Carvalho, Joana Magalhães, Carla Marinho, José Cotter

Open access · diamondAbstract read
In one paragraph

Article in GE Portuguese journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vítor Macedo SilvaGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Marta FreitasGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Sofia XavierGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Pedro Boal CarvalhoGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Joana MagalhãesGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Carla MarinhoGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
José CotterGastroenterology Department, Hospital da Senhora da Oliveira, Guimarães, Portugal.
Hospital da Senhora da Oliveira Guimarães · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Metabolic-associated fatty liver disease (MAFLD) is an increasingly prevalent cause of chronic liver disease. In 2020, the FibroScan-AST (FAST) score was internationally validated as a new tool able to identify patients with steatohepatitis who benefit the most from further therapies, based on liver transient elastography (LTE) findings and serum levels of aspartate aminotransferase (AST). We aimed to identify, in MAFLD patients, which metabolic features may predict a higher FAST score. Methods: Retrospective study of consecutive patients with MAFLD submitted to LTE for two consecutive years. Patients without an AST sample collected within 6 months of the LTE were excluded. FAST score was calculated, stratifying the patient's risk as low (<0.35), medium (0.35-0.67), or high (>0.67). Results: The sample included 117 patients, 53.0% of the female gender, with a mean age of 53 years. On multivariate analysis, patients with type 2 diabetes (T2DM) ( Conclusions: Calculating the FAST score, patients with T2DM presented a significantly higher risk of having significant fibrosis and steatohepatitis. Physicians may rely on this validated instrument to more easily identify which patients with T2DM and MAFLD benefit the most from a specialized follow-up.

Indexed as

HepatologyLiver transient elastographyMetabolic-associated fatty liver disease

Identifiers

PMID38476150
PMCPMC10928873
OpenAlexW4307282717

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.