ArticleAcute and critical care2024
Association of malnutrition status with 30-day mortality in patients with sepsis using objective nutritional indices: a multicenter retrospective study in South Korea.
Article in Acute and critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Prognostic value of nutritional assessment tools in patients with sepsis: a systematic review with meta-analysis of PNI and GNRI.Frontiers in nutrition · 2026Pooled it
- Prognostic value of the prognostic nutritional index in sepsis, pneumonia, and tuberculosis: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Perceived Competence in Nutrition Care Among Hospital Nurses and Its Associated Factors: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Association between energy adequacy and clinical outcomes in septic intensive care unit patients stratified by modified Nutrition Risk in the Critically Ill score.Journal of the Chinese Medical Association : JCMA · 2026Article
- Comparative Prognostic Accuracy of Objective Nutritional Indices in Critically Ill Patients with Sepsis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Prognostic Value of Nutritional Risk Scores in Septic ICU Patients: A Survival Analysis Using mNUTRIC, PNI, and CONUT.Diagnostics (Basel, Switzerland) · 2026Article
- Sepsis in multimorbidity: a domain-based framework for systemic vulnerability and precision care.Frontiers in medicine · 2026Review
- Prognostic nutritional index, Naples prognostic score and Osaka prognostic score as predictors of acute respiratory distress syndrome in non-diabetes mellitus patients with sepsis: a loss of predictive efficacy of NPS and OPS in diabetes mellitus cohorts.Frontiers in endocrinology · 2026Article
- Achieving ≥70% of energy requirements during early enteral nutrition and short-term inflammatory-metabolic profiles in critically ill patients with sepsis: a prospective cohort study.Frontiers in nutrition · 2026Article
- Development and validation of a nomogram for early nutritional risk stratification in elderly patients with pulmonary sepsis: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Lactate-Modified Prognostic Nutritional Index (LPNI) and Its Association with ICU Mortality in Patients with Sepsis: A Retrospective Cohort Study.Journal of inflammation research · 2026Article
- Clinical significance of controlling nutritional status score in predicting ICU admission, prolonged hospitalization, and in-hospital mortality in emergency sepsis: a single-center retrospective study.Frontiers in nutrition · 2026Article
- Prognostic Nutritional Index and Urea-albumin Ratio: Novel Mortality Predictors for Critically Ill Sepsis Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Prognostic value of the advanced lung cancer inflammation index for 28 day mortality in sepsis associated acute kidney injury.Scientific reports · 2025Article
- Can Nutritional Screening Tools Predict the Prognosis of Critically Ill Patients with Sepsis?Medicina (Kaunas, Lithuania) · 2025Observational
- Article
- Relationship between the geriatric nutritional risk index and sepsis in elderly critically ill patients: a retrospective cohort study.European journal of medical research · 2025Article
- The J-shaped association between the ratio of neutrophil counts to prognostic nutritional index and mortality in ICU patients with sepsis: a retrospective study based on the MIMIC database.Frontiers in cellular and infection microbiology · 2025Article
- Prognostic nutritional index as a potential predictor of prognosis in patients with sepsis: a retrospective cohort study.Frontiers in nutrition · 2025Article
- Development and validation of a predictive model for in-hospital mortality from perioperative bacteremia in gastrointestinal surgery.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Controlling Nutritional Status (CONUT) score and the prognostic nutritional index (PNI) have emerged as important nutritional indices because they provide an objective assessment based on data. We aimed to investigate how these nutritional indices relate to outcomes in patients with sepsis.
methodsData were collected retrospectively at five hospitals for patients aged ≥18 years receiving treatment for sepsis between January 1, 2017, and December 31, 2021. Serum albumin and total cholesterol concentrations, and peripheral lymphocytes were used to calculate the CONUT score and PNI. To identify predictors correlated with 30-day mortality, analyses were conducted using univariate and multivariate Cox proportional hazards models.
resultsThe 30-day mortality rate among 9,763 patients was 15.8% (n=1,546). The median CONUT score was 5 (interquartile range [IQR], 3-7) and the median PNI score was 39.6 (IQR, 33.846.4). Higher 30-day mortality rates were associated with individuals with moderate (CONUT score: 5-8; PNI: 35-38) or severe (CONUT: 9-12; PNI: <35) malnutrition compared with those with no malnutrition (CONUT: 0-1; PNI: >38). With CONUT scores, the hazard ratio (HR) associated with moderate malnutrition was 1.52 (95% confidence interval [CI], 1.24-1.87; P<0.001); for severe, HR=2.42 (95% CI, 1.95-3.02; P<0.001). With PNI scores, the HR for moderate malnutrition was 1.29 (95% CI, 1.09-1.53; P=0.003); for severe, HR=1.88 (95% CI, 1.67-2.12; P<0.001).
conclusionsThe nutritional indices CONUT score and PNI showed significant associations with mortality of sepsis patients within 30 days.
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