ArticleEndocrinology, diabetes & metabolism2024
Cushing's Syndrome in Pregnancy Secondary to Adrenocortical Adenoma: A Case Series and Review.
Article in Endocrinology, diabetes & metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- Disease activity and maternal-fetal outcomes in pregnant women with cushing's syndrome: a systematic review and meta‑analysis.Reviews in endocrine & metabolic disorders · 2026Pooled it
- Cushing syndrome manifested during pregnancy and diagnosed following a fragility fracture of the pelvis.JCEM case reports · 2026Article
- Case Report: Reversible central hypothyroidism-like thyroid dysfunction revealing ACTH-independent cushing syndrome during pregnancy.Frontiers in medicine · 2026Article
- Article
- Effectiveness of Medical Treatment on Survivability in Canine Cushing's Syndrome: A Systematic Review and Meta-Analysis.Animals : an open access journal from MDPI · 2025Article
- Diagnosis and Management of Cushing's Syndrome During Pregnancy: Two Cases Report and Literature Review.Clinical case reports · 2025Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo present a case series of Cushing's syndrome (CS) during pregnancy caused by adrenocortical adenomas, highlighting clinical features, hormonal assessments and outcomes.
methodsWe describe five pregnant women with CS, detailing clinical presentations and laboratory findings.
resultsCommon clinical features included a full moon face, buffalo back and severe hypertension. Elevated blood cortisol levels with circadian rhythm disruption and suppressed adrenocorticotrophic hormone (ACTH) levels were observed. Imaging revealed unilateral adrenal tumours. Two cases underwent laparoscopic adrenalectomies during the second trimester, while three had postpartum surgery. All required hormone replacement therapy, with postoperative pathological confirmation of adrenocortical adenomas.
conclusionDiagnosis of CS during pregnancy is challenging due to overlapping features with normal pregnancy: elevated blood cortisol levels and abnormal diurnal rhythm of blood cortisol, suppressed aid diagnosis. Treatment should be individualised due to a lack of explicit optimum therapeutic approaches. Laparoscopic adrenalectomy may be an optimal choice, along with multidisciplinary management including hormone replacement therapy.
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