Evidence map›Paper›PMID 38475842›Full record

ReviewItalian journal of pediatrics2024

Exercise-induced bronchoconstriction, allergy and sports in children.

Angela Klain, Mattia Giovannini, Luca Pecoraro, Simona Barni, Francesca Mori, Lucia Liotti, Carla Mastrorilli, Francesca Saretta, Riccardo Castagnoli, Stefania Arasi and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Italian journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. NOD2-NLRP3 Axis and Asthma.Journal of asthma and allergy · 2025
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Angela KlainDepartment of Woman, Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138, Naples, Italy. klainangela95@gmail.com.ORCID http://orcid.org/0000-0001-7823-2125
Mattia GiovanniniAllergy Unit, Meyer Children's Hospital IRCCS, 50139, Florence, Italy.
Luca PecoraroPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37126, Verona, Italy.
Simona BarniAllergy Unit, Meyer Children's Hospital IRCCS, 50139, Florence, Italy.
Francesca MoriAllergy Unit, Meyer Children's Hospital IRCCS, 50139, Florence, Italy.
Lucia LiottiPediatric Unit, Department of Mother and Child Health, Salesi Children's Hospital, 60123, Ancona, Italy.
Carla MastrorilliPediatric and Emergency Department, Pediatric Hospital Giovanni XXIII, AOU Policlinic of Bari, 70126, Bari, Italy.
Francesca SarettaPediatric Department, Latisana-Palmanova Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100, Udine, Italy.
Riccardo CastagnoliDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100, Pavia, Italy.
Stefania ArasiTranslational Research in Pediatric Specialties Area, Division of Allergy, Bambino Gesù Children's Hospital, IRCCS, 00165, Rome, Italy.
Lucia CaminitiAllergy Unit, Department of Pediatrics, AOU Policlinico Gaetano Martino, 98124, Messina, Italy.
Mariannita GelsominoDepartment of Life Sciences and Public Health, Pediatric Allergy Unit, University Foundation Policlinico Gemelli IRCCS, Catholic University of the Sacred Heart, 00168, Rome, Italy.
Cristiana IndolfiDepartment of Woman, Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138, Naples, Italy.
Michele Miraglia Del GiudiceDepartment of Woman, Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80138, Naples, Italy.
Elio NovembreAllergy Unit, Meyer Children's Hospital IRCCS, 50139, Florence, Italy.
Meyer Children's Hospital · ITUniversity of Campania "Luigi Vanvitelli" · ITAzienda Ospedaliera Universitaria Policlinico "G. Martino" · ITBambino Gesù Children's Hospital · ITOspedale di Latisana · ITOspedale Pediatrico Giovanni XXIII · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Pavia · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise-induced bronchoconstriction (EIB) is characterized by the narrowing of airways during or after physical activity, leading to symptoms such as wheezing, coughing, and shortness of breath. Distinguishing between EIB and exercise-induced asthma (EIA) is essential, given their divergent therapeutic and prognostic considerations. EIB has been increasingly recognized as a significant concern in pediatric athletes. Moreover, studies indicate a noteworthy prevalence of EIB in children with atopic predispositions, unveiling a potential link between allergic sensitivities and exercise-induced respiratory symptoms, underpinned by an inflammatory reaction caused by mechanical, environmental, and genetic factors. Holistic management of EIB in children necessitates a correct diagnosis and a combination of pharmacological and non-pharmacological interventions. This review delves into the latest evidence concerning EIB in the pediatric population, exploring its associations with atopy and sports, and emphasizing the appropriate diagnostic and therapeutic approaches by highlighting various clinical scenarios.

Indexed as

Asthma, Exercise-InducedHypersensitivityHypersensitivity, ImmediateSportsBronchoconstrictionChildExerciseHumansAllergyAsthmaAtopyChildrenDiagnosisExercise-induced asthmaExercise-induced bronchoconstrictionSportTreatment

Identifiers

PMID38475842
PMCPMC10935963
OpenAlexW4392755451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.