Evidence map›Paper›PMID 38475760›Full record

ArticleBMC pulmonary medicine2024

Long-term pulmonary outcomes of young adults born prematurely: a Polish prospective cohort study PREMATURITAS 20.

Katarzyna Walicka-Serzysko, Magdalena Postek, Urszula Borawska-Kowalczyk, Katarzyna Szamotulska, Piotr Kwaśniewicz, Krystyna Polak, Ewa Mierzejewska, Dorota Sands, Magdalena Rutkowska

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Bronchopulmonary dysplasia and extremely preterm birth: time for a broader perspective on long-term outcomes.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
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  7. Chronic lung disease of prematurity and bronchopulmonary dysplasia.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Katarzyna Walicka-SerzyskoCystic Fibrosis Department, Institute of Mother and Child, Warsaw, Poland. katarzyna.walicka@imid.med.pl.
Magdalena PostekCystic Fibrosis Department, Institute of Mother and Child, Warsaw, Poland.
Urszula Borawska-KowalczykCystic Fibrosis Department, Institute of Mother and Child, Warsaw, Poland.
Katarzyna SzamotulskaDepartment of Epidemiology and Biostatistics, Institute of Mother and Child, Warsaw, Poland.
Piotr KwaśniewiczDiagnostic Imaging Department, Institute of Mother and Child, Warsaw, Poland.
Krystyna PolakNeonatology Clinic, Institute of Mother and Child, Warsaw, Poland.
Ewa MierzejewskaDepartment of Epidemiology and Biostatistics, Institute of Mother and Child, Warsaw, Poland.
Dorota SandsCystic Fibrosis Department, Institute of Mother and Child, Warsaw, Poland.
Magdalena RutkowskaDepartment of Epidemiology and Biostatistics, Institute of Mother and Child, Warsaw, Poland.
Cystic Fibrosis Research Foundation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe long-term consequences of prematurity are often not sufficiently recognized. To address this gap, a prospective cohort study, which is a continuation of the multicenter Polish study PREMATURITAS, was conducted, utilizing unique clinical data from 20 years ago.

objectiveThe main goal was to evaluate lung function, detect any structural abnormalities using lung ultrasound, and assess psychological well-being in young adults born between 24 and 34 weeks of gestational age (GA). Additionally, the study aimed to investigate potential associations between perinatal risk factors and abnormalities observed in pulmonary function tests (PFTs) during adulthood.

methodsThe young survivors underwent a comprehensive set of PFTs, a lung ultrasound, along with the quality of life assessment. Information regarding the neonatal period and respiratory complications was obtained from the baseline data collected in the PREMATURITAS study.

resultsA total of 52 young adults, with a mean age of 21.6 years, underwent PFTs. They were divided into two groups based on GA: 24-28 weeks (n = 12) and 29-34 weeks (n = 40). The subgroup born more prematurely had significantly higher lung clearance index (LCI), compared to the other subgroup (p = 0.013). LCI ≥ 6.99 was more frequently observed in the more premature group (50% vs. 12.5%, p = 0.005), those who did not receive prenatal steroids (p = 0.020), with a diagnosis of Respiratory Distress Syndrome (p = 0.034), those who received surfactant (p = 0.026), and mechanically ventilated ≥ 7 days (p = 0.005). Additionally, elevated LCI was associated with the diagnosis of asthma (p = 0.010).

conclusionsThe findings suggest pulmonary effects due to prematurity persist into adulthood and their insult on small airway function. Regular follow-up evaluations of young survivors born preterm should include assessments of PFTs. Specifically, the use of LCI can provide valuable insights into long-term pulmonary impairment.

Indexed as

LungQuality of LifeFemaleHumansInfant, NewbornInfant, PrematurePolandPregnancyProspective StudiesYoung AdultAnxietyDepressionHealth related quality of lifeLung clearance indexPreterm young adultsPulmonary function test

Identifiers

PMID38475760
PMCPMC10935939
OpenAlexW4392691452

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.