ArticleAnnals of geriatric medicine and research2024
Predicting Mortality Risks Using Body Mass Index and Weight Loss at Admission in Patients with Heart Failure.
Article in Annals of geriatric medicine and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Frailty and Recurrent Hospitalization in Older Vietnamese Adults with Heart Failure: A Prospective Cohort Study.Annals of geriatric medicine and research · 2026Article
- Body Mass Index, Clinical Outcomes, and Mortality in Heart Failure: A Mendelian Randomization Study.Journal of the American College of Cardiology · 2026Article
- Association of annual percentage changes in anthropometric indices with all-cause mortality: a 14-year longitudinal study of older US adults.Frontiers in public health · 2026Article
- The association between obesity indicators and mortality among individuals with hyperlipidemia: evidence from the NHANES 2003-2018.Lipids in health and disease · 2025Article
- Novel adiposity indices and their associations with all-cause and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: findings from a nationwide prospective cohort study.Frontiers in endocrinology · 2025Article
- The Link Between Weight-Adjusted-Waist Index and Psoriasis in Adults: A Cross-Sectional Study Based on 2009-2014 and 2003-2006 Data.Clinical, cosmetic and investigational dermatology · 2024Article
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8 authors.
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Abstract
backgroundThe association of the combination of body mass index (BMI) and weight change at admission with prognoses in patients with heart failure (HF) is unclear. Therefore, we investigated whether BMI and weight changes at admission affect mortality in patients with HF.
methodsThis retrospective cohort study lasted 99 months, starting in April 2014, and included 4,862 patients with HF from a Japanese real-world database. Cubic and thin-plate smoothing spline analyses were performed to investigate the association of BMI and weight changes with mortality. The percentage weight change was calculated every 6 months. The study outcome was the presence or absence of death.
resultsThe patients' mean age was 81.5±9.6 years, and 1,239 (25.5%) patients died. Cubic spline analysis revealed a negative correlation of BMI with mortality hazard ratio (HR) (BMI of 18.5 kg/m2 and 25 kg/m2; HR=1.3 [1.2-1.4] and 0.8 [0.7-0.9], respectively). Cubic spline analysis of weight change showed that weight loss tended to increase the mortality HR (each 6% decrease in weight change rate was associated with a 1.1 times higher mortality risk (95% CI [1.0-1.2]) Thin-plate smoothing spline analysis showed that the odds ratio (OR) negatively correlated with BMI (1-year mortality: BMI of 18.5 kg/m2, 22 kg/m2, and 25 kg/m2; OR at 0% weight change=1.5, 1.0, and 0.7, respectively; 2-year mortality: BMI=18.5 kg/m2, 22 kg/m2, and 25 kg/m2; OR at 0% weight change=1.4, 0.9, and 0.7, respectively).
conclusionA low BMI in patients with HF was associated with a higher risk of mortality. Weight loss in patients, regardless of BMI, was associated with a higher OR for mortality.
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