Evidence map›Paper›PMID 38475023›Full record

ArticleSensors (Basel, Switzerland)2024

Near-Infrared Fluorescence Imaging Sensor with Laser Diffuser for Visualizing Photoimmunotherapy Effects under Endoscopy.

Toshihiro Takamatsu, Hideki Tanaka, Tomonori Yano

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Toshihiro TakamatsuExploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa 277-8577, Chiba, Japan.ORCID 0000-0001-7520-089X
Hideki TanakaDepartment of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwa 277-8577, Chiba, Japan.
Tomonori YanoExploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa 277-8577, Chiba, Japan.
Chiba Cancer Center · JPNational Cancer Center Hospital East · JPTokyo University of Science · JP

Funding

National Cancer Center Research and Development Fund 2023-A-9
6 · The paper itself

Abstract

The drug efficacy evaluation of tumor-selective photosensitive substances was expected to be enabled by imaging the fluorescence intensity in the tumor area. However, fluorescence observation is difficult during treatments that are performed during gastrointestinal endoscopy because of the challenges associated with including the fluorescence filter in the camera part. To address this issue, this study developed a device that integrates a narrow camera and a laser diffuser to enable fluorescence imaging through a forceps port. This device was employed to demonstrate that a laser diffuser with an NIR fluorescence imaging sensor could be delivered through a 3.2 mm diameter port. In addition, fluorescence images of Cetuximab-IR700 were successfully observed in two mice, and the fluorescence intensity confirmed that the fluorescence decayed within 330 s. This device is expected to have practical application as a tool to identify the optimal irradiation dose for tumor-selective photosensitive substances under endoscopy.

Indexed as

LightPhototherapyAnimalsCell Line, TumorEndoscopy, GastrointestinalMiceOptical Imagingendoscopeforceps portin vivoNIR fluorescence imagingphotosensitive substance

Identifiers

PMID38475023
PMCPMC10934203
OpenAlexW4392159556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.