Evidence map›Paper›PMID 38474793›Full record

ReviewNutrients2024

Glycemic Changes Related to Arsenic Exposure: An Overview of Animal and Human Studies.

Geovanna Beatriz Oliveira Rosendo, Rannapaula Lawrynhuk Urbano Ferreira, Séphora Louyse Silva Aquino, Fernando Barbosa, Lucia Fatima Campos Pedrosa

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Geovanna Beatriz Oliveira RosendoPostgraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal 59012-570, RN, Brazil.ORCID 0000-0002-2466-5336
Rannapaula Lawrynhuk Urbano FerreiraPostgraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal 59012-570, RN, Brazil.
Séphora Louyse Silva AquinoPostgraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal 59012-570, RN, Brazil.
Fernando BarbosaDepartment of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-903, SP, Brazil.ORCID 0000-0002-2498-0619
Lucia Fatima Campos PedrosaPostgraduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal 59012-570, RN, Brazil.ORCID 0000-0002-5436-5115
Universidade Federal do Rio Grande do Norte · BRUniversidade de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

backgroundArsenic (As) is a risk factor associated with glycemic alterations. However, the mechanisms of action and metabolic aspects associated with changes in glycemic profiles have not yet been completely elucidated. Therefore, in this review, we aimed to investigate the metabolic aspects of As and its mechanism of action associated with glycemic changes.

methodsWe searched the PubMed (MEDLINE) and Google Scholar databases for relevant articles published in English. A combination of free text and medical subject heading keywords and search terms was used to construct search equations. The search yielded 466 articles; however, only 50 were included in the review.

resultsWe observed that the relationship between As exposure and glycemic alterations in humans may be associated with sex, smoking status, body mass index, age, occupation, and genetic factors. The main mechanisms of action associated with changes induced by exposure to As in the glycemic profile identified in animals are increased oxidative stress, reduced expression of glucose transporter type 4, induction of inflammatory factor expression and dysfunction of pancreatic β cells.

conclusionsTherefore, As exposure may be associated with glycemic alterations according to inter-individual differences.

Indexed as

ArsenicAnimalsBlood GlucoseBody Mass IndexHumansPubMedRisk FactorsArsenicBlood Glucosearsenic exposurediabetes mellitusglucose intolerancehyperglycemia

Identifiers

PMID38474793
PMCPMC10934454
OpenAlexW4392239993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.