Evidence map›Paper›PMID 38474762›Full record

ArticleNutrients2024

Effect of Dietary Supplementation with Omega-3 Fatty Acid on the Generation of Regulatory T Lymphocytes and on Antioxidant Parameters and Markers of Oxidative Stress in the Liver Tissue of IL-10 Knockout Mice.

Daniela Dalpubel Campanari, Ualter Guilherme Cipriano, Thais Fernanda de Campos Fraga-Silva, Leandra Náira Zambelli Ramalho, Paula Payão Ovidio, Alceu Afonso Jordão Júnior, Vânia Luiza Deperon Bonato, Eduardo Ferriolli

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Daniela Dalpubel CampanariPostgraduate Program in Clinical Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.
Ualter Guilherme CiprianoBasic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.
Thais Fernanda de Campos Fraga-SilvaDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.ORCID 0000-0002-2053-8938
Leandra Náira Zambelli RamalhoDepartment of Pathology and Legal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.
Paula Payão OvidioDepartment of Health Sciences, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.
Alceu Afonso Jordão JúniorDepartment of Health Sciences, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.ORCID 0000-0003-1288-0802
Vânia Luiza Deperon BonatoBasic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.ORCID 0000-0003-4189-2685
Eduardo FerriolliDepartment of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto 14049-900, Sao Paulo, Brazil.ORCID 0000-0002-5028-2451
Universidade de São Paulo · BR

Funding

National Council for Scientific and Technological Development 166298/2018-2
6 · The paper itself

Abstract

introductionchronic low-grade inflammation, or inflammaging, emerges as a crucial element in the aging process and is associated with cardiovascular and neurological diseases, sarcopenia, and malnutrition. Evidence suggests that omega-3 fatty acids present a potential therapeutic agent in the prevention and treatment of inflammatory diseases, mitigating oxidative stress, and improving muscle mass, attributes that are particularly relevant in the context of aging. The objective of the present study was to evaluate the effectiveness of supplementation with omega-3 fish oil in improving the immune response and oxidative stress in knockout mice for interleukin IL-10 (IL-10 MATERIAL AND

methodsfemale C57BL/6 wild-type (WT) and interleukin IL-10 knockout (IL-10

resultsthe IL-10

conclusionthe findings show a decrease in inflammation, an increase in oxidative stress markers, and a decrease in antioxidant markers in the IL-10

Indexed as

Fatty Acids, Omega-3AnimalsAntioxidantsDietary SupplementsFemaleFish OilsInflammationInterleukin-10LiverMiceMice, Inbred C57BLMice, KnockoutOxidative StressT-Lymphocytes, RegulatoryAntioxidantsFatty Acids, Omega-3Fish OilsInterleukin-10IL−10−/− miceinflammationn-3 PUFAoxidative stress

Identifiers

PMID38474762
PMCPMC10934328
OpenAlexW4392166396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.