Evidence map›Paper›PMID 38474721›Full record

ArticleNutrients2024

Dietary Intervention with Whey Protein Concentrate Does Not Affect Toll-like Receptor Responses and Gene Expression Patterns in Peripheral Blood Mononuclear Cells of Healthy Volunteers.

Mojtaba Porbahaie, Laurien H Ulfman, Andrei Prodan, Malgorzata Teodorowicz, Joyce E L Schloesser, Huub F J Savelkoul, Alwine F M Kardinaal, R J Joost van Neerven

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mojtaba PorbahaieCell Biology and Immunology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.ORCID 0000-0001-6446-9148
Laurien H UlfmanFrieslandCampina, 3818 LE Amersfoort, The Netherlands.
Andrei ProdanNIZO Food Research, 6718 ZB Ede, The Netherlands.
Malgorzata TeodorowiczCell Biology and Immunology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Joyce E L SchloesserNIZO Food Research, 6718 ZB Ede, The Netherlands.
Huub F J SavelkoulCell Biology and Immunology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.ORCID 0000-0001-6236-7092
Alwine F M KardinaalNIZO Food Research, 6718 ZB Ede, The Netherlands.ORCID 0000-0002-2331-2264
R J Joost van NeervenCell Biology and Immunology, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.ORCID 0000-0002-3991-5297
Nederlands Instituut Voor Zuivel Oonderzoek · NLWageningen University & Research · NLFrieslandCampina (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine milk contains bioactive proteins, carbohydrates, and phospholipids with immunomodulatory properties impacting human immunity, potentially contributing to resistance to infections and allergies through diverse mechanisms. One such mechanism is the enhancing of the innate immune response to secondary pathogen-related stimuli, termed innate immune training. Although

Indexed as

Leukocytes, MononuclearToll-Like ReceptorsGene ExpressionHealthy VolunteersHumansImmunoglobulin GMaleWhey ProteinsImmunoglobulin GToll-Like ReceptorsWhey Proteinscytokinedietary interventiongene expressionPBMCsTLR responsewhey protein

Identifiers

PMID38474721
PMCPMC10934438
OpenAlexW4392051695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.