Evidence map›Paper›PMID 38474705›Full record

ArticleNutrients2024

Association between Controlling Nutritional Status (CONUT) Score and Body Composition, Inflammation and Frailty in Hospitalized Elderly Patients.

Aurelio Lo Buglio, Francesco Bellanti, Daniela Francesca Pia Carmignano, Gaetano Serviddio, Gianluigi Vendemiale

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aurelio Lo BuglioDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.ORCID 0000-0003-1569-3658
Francesco BellantiDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.ORCID 0000-0002-8196-7373
Daniela Francesca Pia CarmignanoDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.
Gaetano ServiddioDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.ORCID 0000-0002-6424-7841
Gianluigi VendemialeDepartment of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.
University of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Controlling Nutritional Status (CONUT) score has demonstrated its ability to identify patients with poor nutritional status and predict various clinical outcomes. Our objective was to assess the association between the CONUT score, inflammatory status, and body composition, as well as its ability to identify patients at risk of frailty in hospitalized elderly patients.

methodsa total of 361 patients were retrospectively recruited and divided into three groups based on the CONUT score.

resultspatients with a score ≥5 exhibited significantly higher levels of inflammatory markers, such as erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Neutrophil/Lymphocytes ratio (NLR), main platelet volume (MPV), and ferritin, compared to those with a lower score. Furthermore, these patients showed unfavorable changes in body composition, including a lower percentage of skeletal muscle mass (MM) and fat-free mass (FFM) and a higher percentage of fatty mass (FM). A positive correlation was found between the CONUT score and inflammatory markers, Geriatric Depression Scale Short Form (GDS-SF), and FM. Conversely, the Mini Nutritional Assessment (MNA), Mini-Mental Status Examination, activity daily living (ADL), instrumental activity daily living (IADL), Barthel index, FFM, and MM showed a negative correlation. Frailty was highly prevalent among patients with a higher CONUT score. The receiver operating characteristic (ROC) curve demonstrated high accuracy in identifying frail patients (sensitivity).

conclusionsa high CONUT score is associated with a pro-inflammatory status as well as with unfavorable body composition. Additionally, it is a good tool to identify frailty among hospitalized elderly patients.

Indexed as

FrailtyMalnutritionAgedHumansInflammationNutritional StatusNutrition AssessmentPrognosisRetrospective Studiesbody compositionCONUT scoreelderlyfrailtyhospitalized elderlyinflammationmalnutritionscreening tools

Identifiers

PMID38474705
PMCPMC10935156
OpenAlexW4391960746

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.