Evidence map›Paper›PMID 38474630›Full record

ArticleMolecules (Basel, Switzerland)2024

Targeted Library of Phosphonic-Type Inhibitors of Human Neutrophil Elastase.

Karolina Torzyk-Jurowska, Jaroslaw Ciekot, Lukasz Winiarski

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Karolina Torzyk-JurowskaDivision of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland.ORCID 0000-0003-3432-2529
Jaroslaw CiekotDepartment of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 53-114 Wroclaw, Poland.
Lukasz WiniarskiDivision of Organic and Medicinal Chemistry, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland.ORCID 0000-0002-4351-9414
Wrocław University of Science and Technology · PLLudwik Hirszfeld Institute of Immunology and Experimental Therapy · PL

Funding

National Science Center UMO-2013/09/D/NZ4/02509
6 · The paper itself

Abstract

Despite many years of research, human neutrophil elastase (HNE) still remains an area of interest for many researchers. This multifunctional representative of neutrophil serine proteases is one of the most destructive enzymes found in the human body which can degrade most of the extracellular matrix. Overexpression or dysregulation of HNE may lead to the development of several inflammatory diseases. Previously, we presented the HNE inhibitor with k

Indexed as

Leukocyte ElastaseSerine ProteasesCathepsin GHumansMyeloblastinSerine Proteinase InhibitorsCathepsin GLeukocyte ElastaseMyeloblastinSerine ProteasesSerine Proteinase Inhibitorsneutrophil elastaseproteinase 3α-aminoalkylphosphonates

Identifiers

PMID38474630
PMCPMC10934618
OpenAlexW4392387148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.