Evidence map›Paper›PMID 38474593›Full record

ArticleMolecules (Basel, Switzerland)2024

Preparation and Evaluation of Folate Modified PEG-PLLA Nanoparticles Loaded with Lycorine for Glioma Treatment.

Jieqiong Ding, Jie Su, Binhua Luo, Liqiong Ding

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jieqiong DingDepartment of Physiology, School of Basic Medical Sciences, Hubei University of Science and Technology, Xianning 437100, China.
Jie SuDepartment of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Binhua LuoDepartment of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Liqiong DingDepartment of Pharmaceutics, School of Pharmacy, Hubei University of Science and Technology, Xianning 437100, China.
Hubei University of Science and Technology · CN

Funding

Diabetes Special Fund of Hubei Provincial Key Laboratory of Cardiovascular and Cerebrovascular Diseases in Hubei University of Science and Technology 2023TNB05Initial Scientific Research Fund of Ph.D. in Hubei University of Science and Technology BK202120
6 · The paper itself

Abstract

Lycorine is a kind of natural active ingredient with a strong antitumor effect. In this study, folate ligand-conjugated polyethylene glycol-block-poly(l-lactide) (PEG-PLLA) nanoparticles (FA-PEG-PLLA NPs) were designed to deliver lycorine to enhance its anti-glioma activity. The successful preparation of the FA-PEG-PLLA polymer was confirmed by

Indexed as

Amaryllidaceae AlkaloidsGliomaNanoparticlesPhenanthridinesCell Line, TumorDrug CarriersFolic AcidHumansParticle SizePolyethylene GlycolsReactive Oxygen SpeciesSpectroscopy, Fourier Transform InfraredAmaryllidaceae AlkaloidsDrug CarriersFolic AcidlycorinePhenanthridinesPolyethylene GlycolsReactive Oxygen SpeciesapoptosisFA-PEG-PLLAlycorinenanoparticlesNF-κBROS

Identifiers

PMID38474593
PMCPMC10934019
OpenAlexW4392294753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.