Evidence map›Paper›PMID 38474543›Full record

ArticleMolecules (Basel, Switzerland)2024

The Copper Reduction Potential Determines the Reductive Cytotoxicity: Relevance to the Design of Metal-Organic Antitumor Drugs.

Elena K Beloglazkina, Anna A Moiseeva, Sergey A Tsymbal, Dmitry A Guk, Mikhail A Kuzmin, Olga O Krasnovskaya, Roman S Borisov, Elena S Barskaya, Victor A Tafeenko, Victoria M Alpatova and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Elena K BeloglazkinaDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.ORCID 0000-0001-6796-8241
Anna A MoiseevaDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.
Sergey A TsymbalInternational Institute of Solution Chemistry and Advanced Materials and Technologies, ITMO University, 9 Lomonosov Street, Saint-Petersburg 197101, Russia.ORCID 0000-0003-2230-6767
Dmitry A GukDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.ORCID 0000-0002-5674-8654
Mikhail A KuzminDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.
Olga O KrasnovskayaDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.ORCID 0000-0002-4948-2747
Roman S BorisovTopchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 29 Leninsky Avenue, Moscow 119991, Russia.
Elena S BarskayaDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.
Victor A TafeenkoDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.
Victoria M AlpatovaA.N.Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Bld. 1, 28 Vavilov Street, Moscow 119334, Russia.ORCID 0000-0002-5014-9781
Andrei V ZaitsevA.N.Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Bld. 1, 28 Vavilov Street, Moscow 119334, Russia.ORCID 0000-0001-6448-2561
Alexander V FinkoDepartment of Chemistry, Lomonosov Moscow State University, 1/3 Leninskie Gory, Moscow 119991, Russia.ORCID 0000-0002-1334-9485
Valentina A Ol'shevskayaA.N.Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Bld. 1, 28 Vavilov Street, Moscow 119334, Russia.
Alexander A ShtilBlokhin National Medical Research Center of Oncology, 24 Kashirskoye Shosse, Moscow 115522, Russia.
Lomonosov Moscow State University · RUA. N. Nesmeyanov Institute of Organoelement Compounds · RUITMO University · RURussian Academy of Sciences · RU

Funding

Russian Foundation for Basic Research 19-29-08007
6 · The paper itself

Abstract

Copper-organic compounds have gained momentum as potent antitumor drug candidates largely due to their ability to generate an oxidative burst upon the transition of Cu

Indexed as

Antineoplastic AgentsCoordination ComplexesCopperLigandsOxidation-ReductionReactive Oxygen SpeciesReducing AgentsAntineoplastic AgentsCoordination ComplexesCopperLigandsReactive Oxygen SpeciesReducing Agentsantitumor drug designcoppercytotoxicityelectrochemistrymedicinal chemistryredox reactionstumor cells

Identifiers

PMID38474543
PMCPMC10934576
OpenAlexW4392200475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.