Evidence map›Paper›PMID 38474447›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis and Anti-Inflammatory Activity of Ferulic Acid-Sesquiterpene Lactone Hybrids.

Xiyan Duan, Ning Liu, Ke Lv, Junqi Wang, Mingyue Li, Yanwei Zhang, Xiaoguang Huo, Shiqi Bao, Zhuo Shen, Xuemei Zhang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiyan DuanSchool of Chemistry & Chemical Engineering, Henan University of Science and Technology, Luoyang 471003, China.ORCID 0000-0003-4882-0430
Ning LiuSchool of Nursing, Henan University of Science and Technology, Luoyang 471003, China.
Ke LvThe State Key Laboratory of Medicinal Chemical Biology & College of Chemistry, Nankai University, Tianjin 300071, China.
Junqi WangSchool of Chemistry & Chemical Engineering, Henan University of Science and Technology, Luoyang 471003, China.
Mingyue LiCollege of Pharmacy, Nankai University, Tianjin 300071, China.
Yanwei ZhangAccendatech Company, Ltd., Tianjin 300384, China.
Xiaoguang HuoAccendatech Company, Ltd., Tianjin 300384, China.
Shiqi BaoAccendatech Company, Ltd., Tianjin 300384, China.
Zhuo ShenAccendatech Company, Ltd., Tianjin 300384, China.
Xuemei ZhangAccendatech Company, Ltd., Tianjin 300384, China.

Funding

Scientific and Technological Project of Henan Province 222102310580
6 · The paper itself

Abstract

Acute lung injury (ALI) is a respiratory failure disease associated with high mortality rates in patients. The primary pathological damage is attributed to the excessive release of pro-inflammatory mediators in pulmonary tissue. However, specific therapy for ALI has not been developed. In this study, a series of novel ferulic acid-parthenolide (FA-PTL) and ferulic acid-micheliolide (FA-MCL) hybrid derivatives were designed, synthesized, and evaluated for their anti-inflammatory activities in vitro. Compounds

Indexed as

Acute Lung InjuryCoumaric AcidsSesquiterpenesAnimalsAnti-Inflammatory AgentsCytokinesHumansLactonesLipopolysaccharidesLungMiceAnti-Inflammatory AgentsCoumaric AcidsCytokinesferulic acidLactonesLipopolysaccharidesSesquiterpenesacute lung injuryanti-inflammatory activityferulic acidmicheliolideparthenolide

Identifiers

PMID38474447
PMCPMC10933920

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.