Evidence map›Paper›PMID 38474420›Full record

ArticleCells2024

Nicotinamide Riboside Augments Human Macrophage Migration via SIRT3-Mediated Prostaglandin E2 Signaling.

Jing Wu, Maximilian Bley, Russell S Steans, Allison M Meadows, Rebecca D Huffstutler, Rong Tian, Julian L Griffin, Michael N Sack

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jing WuLaboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10-CRC, Room 5-3342, 10 Center Drive, Bethesda, MD 20892, USA.
Maximilian BleyLaboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10-CRC, Room 5-3342, 10 Center Drive, Bethesda, MD 20892, USA.
Russell S SteansLaboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10-CRC, Room 5-3342, 10 Center Drive, Bethesda, MD 20892, USA.ORCID 0000-0002-0450-3313
Allison M MeadowsLaboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10-CRC, Room 5-3342, 10 Center Drive, Bethesda, MD 20892, USA.
Rebecca D HuffstutlerCardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Rong TianMitochondria and Metabolism Center, Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
Julian L GriffinDepartment of Biochemistry, Cambridge University, Cambridge CB2 1QW, UK.
Michael N SackLaboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10-CRC, Room 5-3342, 10 Center Drive, Bethesda, MD 20892, USA.
National Institutes of Health · USUniversity of Aberdeen · GBUniversity of Washington · US

Funding

Mitochondrial Biology in DiseaseZIAHL005102 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SACK, MICHAEL · 2009 to 2025
$22.7M
Role of intracellular organelle homeostasis in adaptation to dietary restrictive interventionsZIAHL006047 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SACK, MICHAEL · 2010 to 2025
$15.6M
Mechanistic Studies of NAD+/NADH in Human Heart FailureR01HL144937 · NHLBI · UNIVERSITY OF WASHINGTON · PI O'BRIEN, KEVIN D., TIAN, RONG · 2019 to 2023
$4.2M
Mitochondrial biology in diabetesZ01HL005199 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SACK, MICHAEL · 2007 to 2008
$3.5M
Mitochondrial metabolism and macrophage function post MIR01HL149695 · NHLBI · UNIVERSITY OF WASHINGTON · PI TIAN, RONG · 2020 to 2023
$2.9M
Multiplexed UPLC-MS/MS System for Advanced Target MetabolomicsS10OD021562 · OD · UNIVERSITY OF WASHINGTON · PI RAFTERY, DANIEL · 2016 to 2016
$596k
Intramural NIH HHS Z01 HL005199Intramural NIH HHS ZIA HL005102Medical Research Council JLG - MR/P011705/2;NHLBI NIH HHS R01 HL144937NHLBI NIH HHS R01 HL149695NIH HHS S10 OD021562
6 · The paper itself

Abstract

NAD

Indexed as

DinoprostonePyridinium CompoundsSirtuin 3HumansLigandsMacrophagesNiacinamideReceptors, CCR7DinoprostoneLigandsNiacinamidenicotinamide-beta-ribosidePyridinium CompoundsReceptors, CCR7SIRT3 protein, humanSirtuin 3chemotaxismacrophage migrationNAD+ boostingnicotinamide ribosideprostaglandin E2SIRT3

Identifiers

PMID38474420
PMCPMC10931126
OpenAlexW4392460113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.