Evidence map›Paper›PMID 38474309›Full record

ArticleInternational journal of molecular sciences2024

The Potential of Twendee X

Fukka You, Carole Nicco, Yoshiaki Harakawa, Toshikazu Yoshikawa, Haruhiko Inufusa

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Fukka YouDivision of Anti-Oxidant Research, Life Science Research Center, Gifu University, Yanagito 1-1, Gifu 501-1194, Japan.ORCID 0009-0003-2561-0796
Carole NiccoUniversité Paris Cité, 45 Rue des Saints-Pères, 75006 Paris, France.ORCID 0000-0001-8211-2556
Yoshiaki HarakawaDivision of Anti-Oxidant Research, Life Science Research Center, Gifu University, Yanagito 1-1, Gifu 501-1194, Japan.ORCID 0009-0000-0612-7078
Toshikazu YoshikawaLouis Pasteur Center for Medical Research, Tanakamonzen-cho 103-5, Sakyo-ku, Kyoto 606-8225, Japan.
Haruhiko InufusaDivision of Anti-Oxidant Research, Life Science Research Center, Gifu University, Yanagito 1-1, Gifu 501-1194, Japan.ORCID 0009-0004-3355-201X
Louis Pasteur Center for Medical Research · JPGifu University · JPKyoto Prefectural University of Medicine · JPUniversité Paris Cité · FR

Funding

TIMA Establishment (Liechtenstein) 20170101
6 · The paper itself

Abstract

Systemic sclerosis (SSc) is an autoimmune disease characterized by systemic skin hardening, which combines Raynaud's phenomenon and other vascular disorders, skin and internal organ fibrosis, immune disorders, and a variety of other abnormalities. Symptoms vary widely among individuals, and personalized treatment is sought for each patient. Since there is no fundamental cure for SSc, it is designated as an intractable disease with patients receiving government subsidies for medical expenses in Japan. Oxidative stress (OS) has been reported to play an important role in the cause and symptoms of SSc. HOCl-induced SSc mouse models are known to exhibit skin and visceral fibrosis, vascular damage, and autoimmune-like symptoms observed in human SSc. The antioxidant combination Twendee X

Indexed as

AntioxidantsAscorbic AcidCystineGlutamineScleroderma, SystemicAnimalsDietary SupplementsDisease Models, AnimalFibrosisHumansMiceSkinAntioxidantsAscorbic AcidCystineGlutamineTwendee Xantioxidantautoimmunityoxidative stresssystemic sclerosisTwendee X®

Identifiers

PMID38474309
PMCPMC10932212
OpenAlexW4392518808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.