Evidence map›Paper›PMID 38474284›Full record

ArticleInternational journal of molecular sciences2024

RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.

Valérie Fontaine, Thinhinane Boumedine, Elodie Monteiro, Mylène Fournié, Gendre Gersende, José-Alain Sahel, Serge Picaud, Stanislas Veillet, René Lafont, Mathilde Latil and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Valérie FontaineSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Thinhinane BoumedineSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Elodie MonteiroSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.ORCID 0009-0007-0308-0797
Mylène FourniéSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Gendre GersendeSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
José-Alain SahelSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Serge PicaudSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Stanislas VeilletBiophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.
René LafontBiophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.
Mathilde LatilBiophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.ORCID 0000-0002-8424-017X
Pierre J DildaBiophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.ORCID 0000-0001-9916-8513
Serge CameloBiophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.ORCID 0000-0001-8733-8503
Centre National de la Recherche Scientifique · FRSorbonne Université · FR

Funding

Biophytis and Programme Investissements d'Avenir IHU FOReSIGHT. none : private funding and ANR-18-IAHU-01
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarotenoidsMacular Degenerationpara-AminobenzoatesPeroxisome Proliferator-Activated ReceptorsQuinolinesAnti-Inflammatory AgentsDrug Inverse AgonismInflammationRetinoic Acid Receptor alphaRetinoidsRetinoid X ReceptorsTranscriptional ActivationVascular Endothelial Growth Factor A4-(5,6-dihydro-5,5-dimethyl-8-(quinolin-3-yl)naphthalen-2-carboxamido)benzoic acidAnti-Inflammatory AgentsCarotenoidsnorbixinpara-AminobenzoatesPeroxisome Proliferator-Activated ReceptorsQuinolinesRetinoic Acid Receptor alphaRetinoidsRetinoid X ReceptorsVascular Endothelial Growth Factor AangiogenesisinflammationnorbixinN-retinylidene-N-retinylethanolamine (A2E)nuclear receptor (NR)peroxisome proliferator-activated receptor (PPAR)retinal pigment epithelium (RPE)retinoic acid receptor (RAR)retinoic X receptor (RXR)

Identifiers

PMID38474284
PMCPMC10932305
OpenAlexW4392509940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.