Evidence map›Paper›PMID 38474263›Full record

ArticleInternational journal of molecular sciences2024

Hypothermia Inhibits Dexmedetomidine-Induced Contractions in Isolated Rat Aortae.

Soohee Lee, Yeran Hwang, Kyeong-Eon Park, Sungil Bae, Seong-Ho Ok, Seung-Hyun Ahn, Gyujin Sim, Moonju Bae, Ju-Tae Sohn

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Soohee LeeDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Changwon Hospital, Changwon-si 51472, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-6047-633X
Yeran HwangDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Kyeong-Eon ParkDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University College of Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Sungil BaeDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Seong-Ho OkDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Changwon Hospital, Changwon-si 51472, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-1292-7108
Seung-Hyun AhnInstitute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Gyujin SimInstitute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0002-5966-0180
Moonju BaeDepartment of Anesthesiology and Pain Medicine, Gyeongsang National University Hospital, 15 Jinju-daero 816 Beon-gil, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.
Ju-Tae SohnInstitute of Medical Science, Gyeongsang National University, Jinju-si 52727, Gyeongsangnam-do, Republic of Korea.ORCID 0000-0003-0102-5800
Gyeongsang National University Hospital · KRGyeongsang National University · KRChangwon National University · KR

Funding

National Research Foundation of Korea NRF-2021R1F1A1062363, NRF-2021R1I1A3040332, IRIS RS-2023-00238572
6 · The paper itself

Abstract

Dexmedetomidine is widely used to induce sedation in the perioperative period. This study examined the effect of hypothermia (33 and 25 °C) on dexmedetomidine-induced contraction in an endothelium-intact aorta with or without the nitric oxide synthase inhibitor N

Indexed as

DexmedetomidineHypothermiaAnimalsCalciumEndothelium, VascularMuscle ContractionNG-Nitroarginine Methyl EsterProtein Kinase CRatsrho-Associated KinasesCalciumDexmedetomidineNG-Nitroarginine Methyl EsterProtein Kinase Crho-Associated Kinasescalciumcontractiondexmedetomidinehypothermiamyosin light chain

Identifiers

PMID38474263
PMCPMC10931781
OpenAlexW4392472131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.