Evidence map›Paper›PMID 38474237›Full record

ArticleInternational journal of molecular sciences2024

Thermodynamic and Structural Study of Budesonide-Exogenous Lung Surfactant System.

Atoosa Keshavarzi, Ali Asi Shirazi, Rastislav Korfanta, Nina Královič, Mária Klacsová, Juan Carlos Martínez, José Teixeira, Sophie Combet, Daniela Uhríková

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Atoosa KeshavarziDepartment of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.ORCID 0009-0004-9953-8018
Ali Asi ShiraziDepartment of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.
Rastislav KorfantaDepartment of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.
Nina KrálovičDepartment of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.
Mária KlacsováDepartment of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.ORCID 0000-0002-1157-4611
Juan Carlos MartínezALBA Synchrotron, Cerdanyola del Vallés, 08290 Barcelona, Spain.
José TeixeiraLaboratoire Léon-Brillouin (LLB), UMR12 CEA, CNRS, Université Paris-Saclay, F-91191 Gif-sur-Yvette CEDEX, France.
Sophie CombetLaboratoire Léon-Brillouin (LLB), UMR12 CEA, CNRS, Université Paris-Saclay, F-91191 Gif-sur-Yvette CEDEX, France.ORCID 0000-0002-8672-4514
Daniela UhríkováDepartment of Physical Chemistry of Drugs, Faculty of Pharmacy, Comenius University Bratislava, Odbojárov 10, 832 32 Bratislava, Slovakia.ORCID 0000-0002-4397-1283
Comenius University Bratislava · SKCentre National de la Recherche Scientifique · FRALBA Synchrotron (Spain) · ES

Funding

Research Grant Agency of the Ministry of Education and the Slovak Academy of Sciences VEGA 1/0223/20, 1/0305/24Slovak Research and Development Agency APVV-17-0250
6 · The paper itself

Abstract

The clinical benefits of using exogenous pulmonary surfactant (EPS) as a carrier of budesonide (BUD), a non-halogenated corticosteroid with a broad anti-inflammatory effect, have been established. Using various experimental techniques (differential scanning calorimetry DSC, small- and wide- angle X-ray scattering SAXS/WAXS, small- angle neutron scattering SANS, fluorescence spectroscopy, dynamic light scattering DLS, and zeta potential), we investigated the effect of BUD on the thermodynamics and structure of the clinically used EPS, Curosurf

Indexed as

Pulmonary SurfactantsBudesonideCalorimetry, Differential ScanningLipid BilayersLungScattering, Small AngleSurface-Active AgentsThermodynamicsX-Ray DiffractionBudesonideLipid BilayersPulmonary SurfactantsSurface-Active Agentsbudesonidedifferential scanning calorimetrylateral pressurelung surfactantSANSSAXS/WAXS

Identifiers

PMID38474237
PMCPMC10931555
OpenAlexW4392470291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.