Evidence map›Paper›PMID 38474193›Full record

ArticleInternational journal of molecular sciences2024

Neutrophils and NADPH Oxidases Are Major Contributors to Mild but Not Severe Ischemic Acute Kidney Injury in Mice.

Csaba Révész, Tamás Kaucsár, Mária Godó, Krisztián Bocskai, Tibor Krenács, Attila Mócsai, Gábor Szénási, Péter Hamar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Csaba RévészInstitute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Tamás KaucsárInstitute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Mária GodóInstitute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Krisztián BocskaiInstitute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.
Tibor KrenácsDepartment of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0001-9164-065X
Attila MócsaiDepartment of Physiology, Semmelweis University, 1094 Budapest, Hungary.ORCID 0000-0002-0512-1157
Gábor SzénásiInstitute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.ORCID 0000-0002-7350-6091
Péter HamarInstitute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary.ORCID 0000-0002-1095-3564
Semmelweis University · HU

Funding

Hungarian National Research, Development and Innovation Office ANN-110810Hungarian National Research, Development and Innovation Office K-145998Hungarian National Research, Development and Innovation Office KKP-129954Hungarian National Research, Development and Innovation Office SNN-114619
6 · The paper itself

Abstract

Upregulation of free radical-generating NADPH oxidases (NOX), xanthine oxidoreductase (XOR), and neutrophil infiltration-induced, NOX2-mediated respiratory burst contribute to renal ischemia-reperfusion injury (IRI), but their roles may depend on the severity of IRI. We investigated the role of NOX, XOR, and neutrophils in developing IRI of various severities. C57BL/6 and Mcl-1

Indexed as

AcetophenonesAcute Kidney InjuryReperfusion InjuryAnimalsKidneyMiceMice, Inbred C57BLNADPH OxidasesNeutrophilsRNA, MessengerXanthine DehydrogenaseAcetophenonesacetovanilloneNADPH OxidasesRNA, MessengerXanthine Dehydrogenaseacute kidney injuryischemia–reperfusion injuryMcl-1ΔMyeloNADPH oxidaseneutrophil deficiencyoxidative stressreactive oxygen speciesRNA interferencexanthine oxidoreductase

Identifiers

PMID38474193
PMCPMC10932292
OpenAlexW4392375083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.