Evidence map›Paper›PMID 38474099›Full record

ArticleInternational journal of molecular sciences2024

Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia.

David E Phelan, Ben Reddan, Masahiko Shigemura, Jacob I Sznajder, Daniel Crean, Eoin P Cummins

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Beyond Respiration: Rethinking COInternational journal of molecular sciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

David E PhelanSchool of Medicine, University College Dublin, Dublin 4, Ireland.
Ben ReddanSchool of Medicine, University College Dublin, Dublin 4, Ireland.
Masahiko ShigemuraDivision of Thoracic Surgery, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-7767-6584
Jacob I SznajderPulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Daniel CreanConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin 4, Ireland.
Eoin P CumminsSchool of Medicine, University College Dublin, Dublin 4, Ireland.ORCID 0000-0002-9346-8299
University College Dublin · IENorthwestern University · US

Funding

Role of hypercapnia on the lung airwaysR01HL147070 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SZNAJDER, JACOB I · 2019 to 2022
$1.9M
NHLBI NIH HHS R01 HL147070Science Foundation Ireland 15/CDA/3490
6 · The paper itself

Abstract

Hypercapnia occurs when the partial pressure of carbon dioxide (CO

Indexed as

Orphan Nuclear ReceptorsReceptors, SteroidCarbon DioxideDNA-Binding ProteinsHumansHypercapniaMonocytesNuclear Receptor Subfamily 4, Group A, Member 1Nuclear Receptor Subfamily 4, Group A, Member 2Receptors, Thyroid HormoneCarbon DioxideDNA-Binding ProteinsNR4A2 protein, humanNR4A3 protein, humanNuclear Receptor Subfamily 4, Group A, Member 1Nuclear Receptor Subfamily 4, Group A, Member 2Orphan Nuclear ReceptorsReceptors, SteroidReceptors, Thyroid Hormonecarbon dioxideCO2hypercapniaNR4A2NR4A3orphan nuclear receptor family 4ARNA-seqtranscription

Identifiers

PMID38474099
PMCPMC10931687
OpenAlexW4392385475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.