Evidence map›Paper›PMID 38473965›Full record

ReviewInternational journal of molecular sciences2024

TRP Ion Channels in Immune Cells and Their Implications for Inflammation.

Qiyue Yan, Chuanzhou Gao, Mei Li, Rui Lan, Shaohan Wei, Runsong Fan, Wei Cheng

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  17. Underneath the Gut-Brain Axis in IBD-Evidence of the Non-Obvious.International journal of molecular sciences · 2024
    Review
  18. Review
  19. Navigating the Controversies: Role of TRPM Channels in Pain States.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qiyue YanInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.ORCID 0009-0008-0470-8125
Chuanzhou GaoInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Mei LiInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Rui LanInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Shaohan WeiInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Runsong FanInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Wei ChengInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.ORCID 0000-0002-4526-7900
Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transient receptor potential (TRP) ion channels act as cellular sensors and mediate a plethora of physiological processes, including somatosensation, proliferation, apoptosis, and metabolism. Under specific conditions, certain TRP channels are involved in inflammation and immune responses. Thus, focusing on the role of TRPs in immune system cells may contribute to resolving inflammation. In this review, we discuss the distribution of five subfamilies of mammalian TRP ion channels in immune system cells and how these ion channels function in inflammatory mechanisms. This review provides an overview of the current understanding of TRP ion channels in mediating inflammation and may offer potential avenues for therapeutic intervention.

Indexed as

Transient Receptor Potential ChannelsAnimalsHumansImmune SystemInflammationMammalsTransient Receptor Potential Channelsanti-inflammationcytokineimmune cellspro-inflammationTRP ion channel

Identifiers

PMID38473965
PMCPMC10932085
OpenAlexW4392193829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.