Evidence map›Paper›PMID 38473937›Full record

ArticleInternational journal of molecular sciences2024

Independent and Combined Effects of Prenatal Alcohol Exposure and Prenatal Stress on Fetal HPA Axis Development.

Ludmila N Bakhireva, Elizabeth Solomon, Melissa H Roberts, Xingya Ma, Rajani Rai, Alexandria Wiesel, Sandra W Jacobson, Joanne Weinberg, Erin D Milligan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
10.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ludmila N BakhirevaCollege of Pharmacy Substance Use Research and Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
Elizabeth SolomonDepartment of Neurosciences, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.
Melissa H RobertsCollege of Pharmacy Substance Use Research and Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.ORCID 0000-0002-1314-4906
Xingya MaCollege of Pharmacy Substance Use Research and Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
Rajani RaiCollege of Pharmacy Substance Use Research and Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
Alexandria WieselCollege of Pharmacy Substance Use Research and Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
Sandra W JacobsonDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.ORCID 0000-0002-9768-2671
Joanne WeinbergDepartment of Cellular and Physiological Sciences, Faculty of Medicine, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0002-7937-3904
Erin D MilliganDepartment of Neurosciences, University of New Mexico Health Sciences Center, Albuquerque, NM 87106, USA.
University of New Mexico · USUniversity of British Columbia · CAWayne State University · US

Funding

The effect of the COVID-19 pandemic on alcohol use and psycho-somatic health in pregnant and postpartum women with intersecting vulnerabilities.R01AA021771 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BAKHIREVA, LUDMILA NICOLE · 2013 to 2022
$6.5M
NIAAA NIH HHS R01 AA021771NIH HHS R01AA021771
6 · The paper itself

Abstract

Prenatal alcohol exposure (PAE) and prenatal stress (PS) are highly prevalent conditions known to affect fetal programming of the hypothalamic-pituitary-adrenal (HPA) axis. The objectives of this study were to assess the effect of light PAE, PS, and PAE-PS interaction on fetal HPA axis activity assessed via placental and umbilical cord blood biomarkers. Participants of the ENRICH-2 cohort were recruited during the second trimester and classified into the PAE and unexposed control groups. PS was assessed by the Perceived Stress Scale. Placental tissue was collected promptly after delivery; gene and protein analysis for 11

Indexed as

Fetal DiseasesPrenatal Exposure Delayed EffectsPsychological TestsSelf Report11-beta-Hydroxysteroid Dehydrogenase Type 2BiomarkersFemaleFetal DevelopmentHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemPlacentaPregnancyStress, Psychological11-beta-Hydroxysteroid Dehydrogenase Type 2Biomarkersfetal programmingHPA axisplacentapregnancyprenatal alcoholstress

Identifiers

PMID38473937
PMCPMC10932119
OpenAlexW4392168574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.