Evidence map›Paper›PMID 38473902›Full record

ArticleInternational journal of molecular sciences2024

Quantifying the Dynamics of Bacterial Biofilm Formation on the Surface of Soft Contact Lens Materials Using Digital Holographic Tomography to Advance Biofilm Research.

Igor Buzalewicz, Aleksandra Kaczorowska, Wojciech Fijałkowski, Aleksandra Pietrowska, Anna Karolina Matczuk, Halina Podbielska, Alina Wieliczko, Wojciech Witkiewicz, Natalia Jędruchniewicz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Igor BuzalewiczDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wroclaw University of Science and Technology, 50-370 Wroclaw, Poland.ORCID 0000-0002-9774-4625
Aleksandra KaczorowskaDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wroclaw University of Science and Technology, 50-370 Wroclaw, Poland.ORCID 0000-0002-1656-9686
Wojciech FijałkowskiLipoTech Ltd., Liszki 536, 32-060 Liszki, Poland.
Aleksandra PietrowskaDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wroclaw University of Science and Technology, 50-370 Wroclaw, Poland.ORCID 0000-0003-4030-188X
Anna Karolina MatczukDepartment of Pathology, Division of Microbiology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 31 C.K. Norwida St., 51-375 Wroclaw, Poland.ORCID 0000-0002-7282-6560
Halina PodbielskaDepartment of Biomedical Engineering, Faculty of Fundamental Problems of Technology, Wroclaw University of Science and Technology, 50-370 Wroclaw, Poland.ORCID 0000-0001-7162-8530
Alina WieliczkoDepartment of Epizootiology and Veterinary Administration with Clinic of Infectious Diseases, Wroclaw University of Environmental and Life Sciences, 45 Grunwaldzki Square, 50-366 Wroclaw, Poland.ORCID 0000-0001-7018-6507
Wojciech WitkiewiczResearch and Development Centre, Regional Specialist Hospital in Wroclaw, 73A H. M. Kamienskiego St., 51-124 Wroclaw, Poland.
Natalia JędruchniewiczResearch and Development Centre, Regional Specialist Hospital in Wroclaw, 73A H. M. Kamienskiego St., 51-124 Wroclaw, Poland.
Wrocław University of Science and Technology · PLWroclaw Research Centre EIT+ (Poland) · PLWrocław University of Environmental and Life Sciences · PL

Funding

National Center for Research and Development POIR.04.01.01-00-0016/19-00National Center of Science 2021/41/B/ST7/04002
6 · The paper itself

Abstract

The increase in bacterial resistance to antibiotics in recent years demands innovative strategies for the detection and combating of biofilms, which are notoriously resilient. Biofilms, particularly those on contact lenses, can lead to biofilm-related infections (e.g., conjunctivitis and keratitis), posing a significant risk to patients. Non-destructive and non-contact sensing techniques are essential in addressing this threat. Digital holographic tomography emerges as a promising solution. This allows for the 3D reconstruction of the refractive index distribution in biological samples, enabling label-free visualization and the quantitative analysis of biofilms. This tool provides insight into the dynamics of biofilm formation and maturation on the surface of transparent materials. Applying digital holographic tomography for biofilm examination has the potential to advance our ability to combat the antibiotic bacterial resistance crisis. A recent study focused on characterizing biofilm formation and maturation on six soft contact lens materials (three silicone hydrogels, three hydrogels), with a particular emphasis on

Indexed as

BiofilmsContact Lenses, HydrophilicAnti-Bacterial AgentsBacteriaHumansHydrogelsPseudomonas aeruginosaAnti-Bacterial AgentsHydrogelsbacterial biofilmsdigital holographic tomographydynamics of biofilm formationP. aeruginosaquantitative phase imagingS. epidermidissoft contact lenses

Identifiers

PMID38473902
PMCPMC10932241
OpenAlexW4392157254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.