Evidence map›Paper›PMID 38473868›Full record

ReviewInternational journal of molecular sciences2024

HIV Reservoirs and Treatment Strategies toward Curing HIV Infection.

Kouki Matsuda, Kenji Maeda

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Analytical and Clinical Performance of VIDASDiagnostics (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Searching for a HIV-1 Cure.Theranostics · 2026
    Review
  14. Article
  15. Review
  16. Article
  17. Immuno-cell metabolic changes in HIV-1 infection.Infectious diseases & immunity · 2025
    Review
  18. Review
  19. Engineering of CD8mBio · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kouki MatsudaJoint Research Center for Human Retrovirus Infection, Kagoshima University, Kagoshima 890-8544, Japan.
Kenji MaedaJoint Research Center for Human Retrovirus Infection, Kagoshima University, Kagoshima 890-8544, Japan.

Funding

Japan Society for the Promotion of Science 20K17480 23K15385 23K07944National Center for Global Health and Medicine 22A2005
6 · The paper itself

Abstract

Combination antiretroviral therapy (cART) has significantly improved the prognosis of individuals living with human immunodeficiency virus (HIV). Acquired immunodeficiency syndrome has transformed from a fatal disease to a treatable chronic infection. Currently, effective and safe anti-HIV drugs are available. Although cART can reduce viral production in the body of the patient to below the detection limit, it cannot eliminate the HIV provirus integrated into the host cell genome; hence, the virus will be produced again after cART discontinuation. Therefore, research into a cure (or remission) for HIV has been widely conducted. In this review, we focus on drug development targeting cells latently infected with HIV and assess the progress including our current studies, particularly in terms of the "Shock and Kill", and "Block and Lock" strategies.

Indexed as

Acquired Immunodeficiency SyndromeAnti-HIV AgentsHIV-1HIV InfectionsCD4-Positive T-LymphocytesHumansVirus ActivationVirus LatencyAnti-HIV AgentsBlock and LockHIVHIV cureHIV reservoirlatency-reversing agentsShock and Kill

Identifiers

PMID38473868
PMCPMC10932120

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.