Evidence map›Paper›PMID 38473791›Full record

ReviewInternational journal of molecular sciences2024

The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia.

Raquel Cuevas-Diaz Duran, Emmanuel Martinez-Ledesma, Melissa Garcia-Garcia, Denisse Bajo Gauzin, Andrea Sarro-Ramírez, Carolina Gonzalez-Carrillo, Denise Rodríguez-Sardin, Alejandro Fuentes, Alejandro Cardenas-Lopez

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
24.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  18. The Potential of Hair Matrix for Biomarker Analysis in Schizophrenia.International journal of molecular sciences · 2025
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Raquel Cuevas-Diaz DuranTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey 64710, NL, Mexico.ORCID 0000-0003-4257-3184
Emmanuel Martinez-LedesmaTecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Monterrey 64710, NL, Mexico.
Melissa Garcia-GarciaCapilarFix®, Monterrey 66220, NL, Mexico.
Denisse Bajo GauzinCapilarFix®, Monterrey 66220, NL, Mexico.
Andrea Sarro-RamírezCapilarFix®, Monterrey 66220, NL, Mexico.
Carolina Gonzalez-CarrilloCapilarFix®, Monterrey 66220, NL, Mexico.
Denise Rodríguez-SardinCapilarFix®, Monterrey 66220, NL, Mexico.
Alejandro FuentesCapilarFix®, Monterrey 66220, NL, Mexico.
Alejandro Cardenas-LopezCapilarFix®, Monterrey 66220, NL, Mexico.
Tecnológico de Monterrey · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Androgenetic alopecia is a highly prevalent condition mainly affecting men. This complex trait is related to aging and genetics; however, multiple other factors, for example, lifestyle, are also involved. Despite its prevalence, the underlying biology of androgenetic alopecia remains elusive, and thus advances in its treatment have been hindered. Herein, we review the functional anatomy of hair follicles and the cell signaling events that play a role in follicle cycling. We also discuss the pathology of androgenetic alopecia and the known molecular mechanisms underlying this condition. Additionally, we describe studies comparing the transcriptional differences in hair follicles between balding and non-balding scalp regions. Given the genetic contribution, we also discuss the most significant risk variants found to be associated with androgenetic alopecia. A more comprehensive understanding of this pathology may be generated through using multi-omics approaches.

Indexed as

AlopeciaHair FollicleAgingGenomicsHumansLife StyleMaleandrogenetic alopeciagenomicstranscriptomics

Identifiers

PMID38473791
PMCPMC10932098
OpenAlexW4392057705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.