Evidence map›Paper›PMID 38473750›Full record

ArticleInternational journal of molecular sciences2024

Impact of Immunopathy and Coagulopathy on Multi-Organ Failure and Mortality in a Lethal Porcine Model of Controlled and Uncontrolled Hemorrhage.

Milomir O Simovic, James Bynum, Bin Liu, Jurandir J Dalle Lucca, Yansong Li

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Milomir O SimovicUS Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.
James BynumUS Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.
Bin LiuUS Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.
Jurandir J Dalle LuccaUS Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.
Yansong LiUS Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA.ORCID 0000-0002-8341-1539
The University of Texas Health Science Center at San Antonio · USUnited States Army Institute of Surgical Research · US

Funding

United States Department of Defense W81XWH190040United States Department of Defense W81XWH200040
6 · The paper itself

Abstract

Uncontrolled hemorrhage is a major preventable cause of death in patients with trauma. However, the majority of large animal models of hemorrhage have utilized controlled hemorrhage rather than uncontrolled hemorrhage to investigate the impact of immunopathy and coagulopathy on multi-organ failure (MOF) and mortality. This study evaluates these alterations in a severe porcine controlled and uncontrolled hemorrhagic shock (HS) model. Anesthetized female swine underwent controlled hemorrhage and uncontrolled hemorrhage by partial splenic resection followed with or without lactated Ringer solution (LR) or Voluven

Indexed as

AcidosisBlood Coagulation DisordersShock, HemorrhagicAnimalsCytokinesFemaleHemorrhageHumansMultiple Organ FailureSwineCytokinescoagulopathydamage control resuscitationimmunopathyMOFmortalityswineuncontrolled hemorrhagic shock

Identifiers

PMID38473750
PMCPMC10931034
OpenAlexW4391998450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.