Evidence map›Paper›PMID 38473746›Full record

ArticleInternational journal of molecular sciences2024

Protective Effects of Inulin on Stress-Recurrent Inflammatory Bowel Disease.

Yao Du, Kanta Kusama, Koki Hama, Xinyue Chen, Yu Tahara, Susumu Kajiwara, Shigenobu Shibata, Kanami Orihara

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Progress in interventions for vaginal microecology.Frontiers in cellular and infection microbiology · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yao DuSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama 226-8501, Japan.
Kanta KusamaLaboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan.
Koki HamaLaboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan.
Xinyue ChenSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama 226-8501, Japan.ORCID 0000-0001-9276-8209
Yu TaharaLaboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan.ORCID 0000-0002-3015-8883
Susumu KajiwaraSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama 226-8501, Japan.
Shigenobu ShibataLaboratory of Physiology and Pharmacology, School of Advanced Science and Engineering, Waseda University, Tokyo 162-8480, Japan.ORCID 0000-0002-6177-1963
Kanami OriharaSchool of Life Science and Technology, Tokyo Institute of Technology, Yokohama 226-8501, Japan.ORCID 0000-0002-2652-4529
Tokyo Institute of Technology · JPHiroshima University · JPWaseda University · JP

Funding

Japan Science and Technology Agency JPMJFR205GJapan Society for the Promotion of Science JP20K07535Kobayashi Foundation Research Grant 2021FY
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the digestive tract and is closely associated with the homeostasis of the gut microbiota. Inulin, as a natural prebiotic, displays anti-inflammatory activity and maintains equilibrium of the intestinal microbiota. In this study, our research aimed to explore the potential of inulin in enhancing intestinal immunity and reducing inflammation in stress-recurrent IBD. In this study, a co-culture intestinal epithelium model and a stress-recurrent IBD mouse model was used to examine the protective effects of inulin. It was observed that inulin digesta significantly reduced pro-inflammatory cytokine expression (

Indexed as

Inflammatory Bowel DiseasesInulinAnimalsColonCytokinesInflammationMiceCytokinesInulincytokinesER stressIBDinulinmucinSCFAsstress

Identifiers

PMID38473746
PMCPMC10931620
OpenAlexW4391998190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.