Evidence map›Paper›PMID 38473390›Full record

ReviewCancers2024

Role of Non-Coding RNAs in Diagnosis, Prediction and Prognosis of Multiple Myeloma.

Maciej Dubaj, Karol Bigosiński, Aleksandra Dembowska, Radosław Mlak, Aneta Szudy-Szczyrek, Teresa Małecka-Massalska, Iwona Homa-Mlak

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maciej DubajStudent Scientific Group, Department of Human Physiology, Medical University of Lublin, 20-080 Lublin, Poland.ORCID 0000-0003-4709-8677
Karol BigosińskiStudent Scientific Group, Department of Human Physiology, Medical University of Lublin, 20-080 Lublin, Poland.ORCID 0000-0003-3613-3772
Aleksandra DembowskaStudent Scientific Group, Department of Human Physiology, Medical University of Lublin, 20-080 Lublin, Poland.ORCID 0000-0002-2011-7420
Radosław MlakDepartment of Laboratory Diagnostics, Medical University of Lublin, Doktora Witolda Chodźki 1 Str., 20-093 Lublin, Poland.ORCID 0000-0001-7399-8340
Aneta Szudy-SzczyrekDepartment of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, 20-081 Lublin, Poland.
Teresa Małecka-MassalskaDepartment of Human Physiology, Medical University of Lublin, 20-080 Lublin, Poland.
Iwona Homa-MlakDepartment of Human Physiology, Medical University of Lublin, 20-080 Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is the second most common hematologic malignancy in the world and accounts for 15% of primary hemocytopathies, with an ever-increasing number of new cases. It is asymptomatic in 30% of instances; hence, the determination of highly sensitive and specific markers is necessary to make a proper diagnosis. In the last 20 years, miRNAs, involved in regulating the expression of genes responsible for cell proliferation and differentiation, including tumor cells, have been identified as potential diagnostic and prognostic markers. The main aim of the following review was to outline the role of miRNAs in the diagnosis and prognosis of MM, considering their role in the pathogenesis of the disease and identifying their target genes and pathways. For this purpose, publications dating from 2013-2023 have been reviewed. Based on the available data, it is concluded that non-coding RNAs including miRNAs could be potential markers in MM. Furthermore, they may serve as therapeutic targets for certain drugs.

Indexed as

cancerdiagnosismiRNAsmultiple myelomaprognosis

Identifiers

PMID38473390
PMCPMC10931522
OpenAlexW4392376186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.