Evidence map›Paper›PMID 38473332›Full record

ArticleCancers2024

The Disproportionate Rise in Pancreatic Cancer in Younger Women Is Due to a Rise in Adenocarcinoma and Not Neuroendocrine Tumors: A Nationwide Time-Trend Analysis Using 2001-2018 United States Cancer Statistics Databases.

Yi Jiang, Yazan Abboud, Jeff Liang, Brent Larson, Arsen Osipov, Jun Gong, Andrew E Hendifar, Katelyn Atkins, Quin Liu, Nicholas N Nissen and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yi JiangKarsh Division of Gastroenterology, Departments of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-5114-0183
Yazan AbboudKarsh Division of Gastroenterology, Departments of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Jeff LiangKarsh Division of Gastroenterology, Departments of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Brent LarsonDepartment of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Arsen OsipovDivision of Medical Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Jun GongDivision of Medical Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-8713-1406
Andrew E HendifarDivision of Medical Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Katelyn AtkinsDepartment of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Quin LiuKarsh Division of Gastroenterology, Departments of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0002-3880-8027
Nicholas N NissenDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Debiao LiBiomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.
Stephen J PandolKarsh Division of Gastroenterology, Departments of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0003-0818-6017
Simon K LoKarsh Division of Gastroenterology, Departments of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Srinivas GaddamKarsh Division of Gastroenterology, Departments of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.ORCID 0000-0001-6818-6305
Cedars-Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In previous studies, a significant increase in the incidence of pancreatic cancer among younger women compared to men in the United States was noted. However, the specific histopathologic characteristics were not delineated. This population-based study aimed to assess whether this disproportionate rise in pancreatic cancer in younger women was contributed by pancreatic ductal adenocarcinoma (PDAC) or pancreatic neuroendocrine tumors (PanNET). The United States Cancer Statistics (USCS) database was used to identify patients with pancreatic cancer between 2001 and 2018. The results showed that, in younger adults, the incidence of PDAC has increased in women [average annual percentage change (AAPC) = 0.62%], while it has remained stable in men (AAPC = -0.09%). The PDAC incidence rate among women increased at a greater rate compared to men with a statistically significant difference in AAPC (

Indexed as

pancreatic ductal adenocarcinomapancreatic neuroendocrine tumorssex disparity

Identifiers

PMID38473332
PMCPMC10931165
OpenAlexW4392232738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.