Evidence map›Paper›PMID 38473316›Full record

ArticleCancers2024

Lifestyle Factors and Breast Cancer in Females with PTEN Hamartoma Tumor Syndrome (PHTS).

Linda A J Hendricks, Katja C J Verbeek, Janneke H M Schuurs-Hoeijmakers, Arjen R Mensenkamp, Hilde Brems, Robin de Putter, Violetta C Anastasiadou, Marie-Charlotte Villy, Arne Jahn, Verena Steinke-Lange and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Linda A J HendricksDepartment of Human Genetics, Radboudumc Expert Center for PHTS, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0002-1008-0265
Katja C J VerbeekDepartment of Human Genetics, Radboudumc Expert Center for PHTS, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-5981-6301
Janneke H M Schuurs-HoeijmakersDepartment of Human Genetics, Radboudumc Expert Center for PHTS, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Arjen R MensenkampDepartment of Human Genetics, Radboudumc Expert Center for PHTS, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0003-3805-877X
Hilde BremsDepartment of Human Genetics, University of Leuven, 3000 Leuven, Belgium.
Robin de PutterCenter for Medical Genetics, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0001-9410-8941
Violetta C AnastasiadouKaraiskakio Foundation, Nicosia Cyprus and Archbishop Makarios III Children's Hospital, Nicosia 2012, Cyprus.
Marie-Charlotte VillyService de Génétique, Institut Curie, 75248 Paris, France.
Arne JahnInstitute for Clinical Genetics, Faculty of Medicine Carl Gustav Carus, Technische Universitat Dresden, 01062 Dresden, Germany.ORCID 0000-0003-1045-1908
Verena Steinke-LangeMedical Genetics Center, 80335 Munich, Germany.ORCID 0000-0001-8491-3234
Margherita BaldassarriMedical Genetics, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-0391-1980
Arvids IrmejsInstitute of Oncology, Riga Stradins University, 1007 Riga, Latvia.ORCID 0000-0002-0538-1194
Mirjam M de JongDepartment of Genetics, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Thera P LinksDepartment of Endocrinology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Edward M LeterDepartment of Clinical Genetics, Maastricht University Medical Center, 6229 ER Maastricht, The Netherlands.
Daniëlle G M BoschDepartment of Clinical Genetics, Erasmus MC Rotterdam, 3015 GD Rotterdam, The Netherlands.
Hildegunn Høberg-VettiWestern Norway Familial Cancer Center, Department of Medical Genetics, Haukeland University Hospital, 5021 Bergen, Norway.ORCID 0000-0002-9876-576X
Marianne Tveit HaavindWestern Norway Familial Cancer Center, Department of Medical Genetics, Haukeland University Hospital, 5021 Bergen, Norway.
Kjersti JørgensenDepartment of Medical Genetics, Oslo University Hospital, 0450 Oslo, Norway.
Lovise MæhleDepartment of Medical Genetics, Oslo University Hospital, 0450 Oslo, Norway.
Ana BlatnikDepartment of Clinical Cancer Genetics, Institute of Oncology Ljubljana, 1000 Ljubljana, Slovenia.
Joan BrunetHereditary Cancer Program, Catalan Institute of Oncology, IDIBELL-IDIBGI, 08916 Barcelona, Spain.ORCID 0000-0003-1945-3512
Esther DarderHereditary Cancer Program, Catalan Institute of Oncology, IDIBELL-IDIBGI, 08916 Barcelona, Spain.ORCID 0000-0002-7764-1397
Emma ThamDepartment of Clinical Genetics, Karolinska University Hospital, 14186 Stockholm, Sweden.ORCID 0000-0001-6079-164X
Nicoline HoogerbruggeDepartment of Human Genetics, Radboudumc Expert Center for PHTS, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0003-2393-8141
Janet R VosDepartment of Human Genetics, Radboudumc Expert Center for PHTS, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0001-8802-7002

Funding

PTEN Research Foundation 17-002Region Stockholm FoUI-973659
6 · The paper itself

Abstract

Females with PTEN Hamartoma Tumor Syndrome (PHTS) have breast cancer risks up to 76%. This study assessed associations between breast cancer and lifestyle in European female adult PHTS patients. Data were collected via patient questionnaires (July 2020-March 2023) and genetic diagnoses from medical files. Associations between lifestyle and breast cancer were calculated using logistic regression corrected for age. Index patients with breast cancer before PHTS diagnosis (breast cancer index) were excluded for ascertainment bias correction. In total, 125 patients were included who completed the questionnaire at a mean age of 44 years (SD = 13). This included 21 breast cancer indexes (17%) and 39 females who developed breast cancer at 43 years (SD = 9). Breast cancer patients performed about 1.1 times less often 0-1 times/week physical activity than ≥2 times (OR

Indexed as

alcohol drinkingbody mass indexbreast neoplasmexercisehamartoma syndromemultiple

Identifiers

PMID38473316
PMCPMC10930780

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.