Evidence map›Paper›PMID 38473302›Full record

ReviewCancers2024

ctDNA for the Evaluation and Management of EGFR-Mutant Non-Small Cell Lung Cancer.

Aakash Desai, Tadana A Vázquez, Keishla M Arce, Marcelo Corassa, Philip C Mack, Jhanelle E Gray, Bruna Pellini

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Aakash DesaiDivision of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-2943-3817
Tadana A VázquezSchool of Medicine, Ponce Health Sciences University, Ponce, PR 00716, USA.ORCID 0000-0001-8548-4478
Keishla M ArceSchool of Medicine, Ponce Health Sciences University, Ponce, PR 00716, USA.
Marcelo CorassaThoracic Oncology Unit, BP-A Beneficência Portuguesa de São Paulo, São Paulo 01323-001, Brazil.ORCID 0000-0002-7707-8768
Philip C MackCenter for Thoracic Oncology, The Tisch Cancer Institute, Mount Sinai Health System, New York, NY 10029, USA.
Jhanelle E GrayDepartment of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Bruna PelliniDepartment of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.ORCID 0000-0003-0898-0202
Ponce Health Sciences University · PRUniversity of South Florida · USBeneficência Portuguesa de São Paulo · BRMount Sinai Health System · USUniversity of Alabama at Birmingham · US

Funding

Bristol Myers Squibb Foundation 69-22202-01-01
6 · The paper itself

Abstract

Circulating tumor DNA (ctDNA) offers a new paradigm in optimizing treatment strategies for epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC). Its potential spans early-stage disease, influencing adjuvant therapy, to advanced disease, where it aids in identifying genomic markers and resistance mechanisms. This review explores the evolving landscape of utilizing liquid biopsies, specifically circulating tumor DNA (ctDNA), in the management of NSCLC with

Indexed as

ctDNAEGFRmolecular responseMRD

Identifiers

PMID38473302
PMCPMC10930898
OpenAlexW4392169586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.