Evidence map›Paper›PMID 38472968›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Dual-Energy CT Iodine Uptake of Head and Neck: Definition of Reference Values in a Big Data Cohort.

Ibrahim Yel, Giuseppe Mauro Bucolo, Scherwin Mahmoudi, Vitali Koch, Aynur Gökduman, Tommaso D Angelo, Leon David Grünewald, Mirela Dimitrova, Katrin Eichler, Thomas J Vogl and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Ibrahim YelGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.ORCID 0000-0002-3894-4782
Giuseppe Mauro BucoloDepartment of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-2076-5532
Scherwin MahmoudiGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.
Vitali KochGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.ORCID 0000-0001-6915-5906
Aynur GökdumanGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.
Tommaso D AngeloDepartment of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, 98122 Messina, Italy.ORCID 0000-0003-0004-6378
Leon David GrünewaldGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.
Mirela DimitrovaGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.ORCID 0000-0002-6905-8556
Katrin EichlerGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.
Thomas J VoglGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.ORCID 0000-0001-5218-1075
Christian BoozGoethe University Frankfurt, University Hospital Frankfurt, Clinic for Radiology and Nuclear Medicine, 60590 Frankfurt, Germany.
Goethe University Frankfurt · DEUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite a considerable amount of literature on dual-energy CT (DECT) iodine uptake of the head and neck, the physiologic iodine uptake of this region has not been defined yet. This study aims to establish reference values for the iodine uptake of healthy organs to facilitate clinical application.

methodsConsecutive venous DECT scans of the head and neck were reviewed, and unremarkable exams were included (

resultsOverall mean iodine uptake values ranged between 0.5 and 9.4 mg/mL. Women showed higher iodine concentrations in the cervical vessels and higher uptake for the parotid gland, masseter muscle, submandibular glands, sublingual glands, palatine tonsils, tongue body, thyroid gland, and the sternocleidomastoid muscle than men (

conclusionphysiologic iodine uptake values of cervical organs and tissues show gender-, age-, and BMI-related differences, which should be considered in the clinical routine of head and neck DECT.

Indexed as

computed tomographyhead and neck imagingiodine contrast mediaiodine quantificationiodine uptake reference values

Identifiers

PMID38472968
PMCPMC10930839
OpenAlexW4392155904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.