Evidence map›Paper›PMID 38472652›Full record

ReviewMolecular neurobiology2024

The Role of Dietary Peptides Gluten and Casein in the Development of Autism Spectrum Disorder: Biochemical Perspectives.

Geir Bjørklund, Nagwa A Meguid, Maha Hemimi, Elen Sahakyan, Katarine Fereshetyan, Konstantin Yenkoyan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Zinc deficiency and zinc/copper ratio imbalance in autism spectrum disorder: a reanalysis of six multinational studies.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Geir BjørklundCouncil for Nutritional and Environmental Medicine (CONEM), Toften 24, 8610, Mo i Rana, Norway. bjorklund@conem.org.ORCID http://orcid.org/0000-0003-2632-3935
Nagwa A MeguidResearch on Children with Special Needs Department, National Research Centre, Giza, Egypt.
Maha HemimiResearch on Children with Special Needs Department, National Research Centre, Giza, Egypt.
Elen SahakyanNeuroscience Laboratory, Cobrain Center, Yerevan State Medical University after M. Heratsi, 2 Koryun, 0025, Yerevan, Armenia.
Katarine FereshetyanNeuroscience Laboratory, Cobrain Center, Yerevan State Medical University after M. Heratsi, 2 Koryun, 0025, Yerevan, Armenia.
Konstantin YenkoyanNeuroscience Laboratory, Cobrain Center, Yerevan State Medical University after M. Heratsi, 2 Koryun, 0025, Yerevan, Armenia. konstantin.yenkoyan@meduni.am.
Yerevan State Medical University · AMNational Research Centre · EGThe Research Council of Norway · NO

Funding

State Committee of Science 20TTCG-3A012 and N10-14/I-1
6 · The paper itself

Abstract

This paper examines the role of dietary peptides gluten and casein in modulating brain function in individuals with autism spectrum disorder (ASD) from a biochemical perspective. Neurotransmitter systems and neural networks are crucial for brain function, and alterations at the biochemical level can contribute to the characteristic symptoms and behaviors of ASD. The paper explores how dietary peptides influence neurotransmitter systems and neural networks, highlighting their potential as interventions to improve brain function in ASD. The evidence suggests that dietary peptides can impact neurotransmitter synthesis, release, and receptor interactions, disrupting the balance of neurotransmitter systems and affecting neural network function. The findings underscore the potential of dietary interventions in modulating brain function in ASD and call for further research to elucidate the underlying mechanisms and optimize clinical practice. Considering individual dietary sensitivities and preferences, personalized dietary approaches may be necessary for optimal outcomes. Dietary interventions' timing, duration, and integration with other evidence-based treatments are crucial considerations. Safety considerations and regular monitoring are important to ensure the implementation of dietary interventions safely and effectively.

Indexed as

Autism Spectrum DisorderCaseinsGlutensAnimalsBrainHumansNeurotransmitter AgentsCaseinsGlutensNeurotransmitter AgentsAutism spectrum disorderBiochemical alterationsCaseinDietary peptidesGlutenNeural networksNeurotransmitter systemsPersonalized nutrition

Identifiers

PMID38472652
OpenAlexW4392683052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.