Evidence map›Paper›PMID 38472519›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Unmasking Bartonella henselae infection in the shadows of long COVID thanks to clinical metagenomics.

Aurélien Aubry, Emilie Corvilain, Théo Ghelfenstein-Ferreira, François Camelena, Véronique Meignin, Béatrice Berçot, Jérôme Le Goff, Maud Salmona

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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Autonomic Dysfunction in Patients withPathogens (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Experimental Infection of Ferrets withPathogens (Basel, Switzerland) · 2025
    Article
  5. Journal of central nervous system disease · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aurélien AubryVirology Department, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France. aubry.aurelien@chu-amiens.fr.
Emilie CorvilainClinical Immunology Department, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Théo Ghelfenstein-FerreiraParasitology-Mycology Department, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
François CamelenaBacteriology Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Véronique MeigninPathology Department, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Béatrice BerçotBacteriology Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Jérôme Le GoffVirology Department, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Maud SalmonaVirology Department, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of long COVID often relies on symptoms post-COVID-19, occasionally lacking biological evidence. This case study illustrates how investigating long COVID uncovered an underlying bartonellosis through clinical metagenomics. Following mild COVID-19, a 26-year-old woman experienced persistent symptoms during 5 months, including axillary adenopathy. Pathological examination, 16 S rRNA PCR, and clinical metagenomic analysis were done on an adenopathy biopsy. The latter revealed Bartonella henselae DNA and RNA. Treatment with clarithromycin improved symptoms. This case underscores the relevance of clinical metagenomics in diagnosing hidden infections. Post-COVID symptoms warrant thorough investigation, and bartonellosis should be considered in polyadenopathy cases, regardless of a recent history of cat or flea exposures.

Indexed as

Bartonella henselaeCOVID-19MetagenomicsAdultAnti-Bacterial AgentsClarithromycinFemaleHumansSARS-CoV-2Anti-Bacterial AgentsClarithromycinBartonellosisCat scratch diseaseLong COVIDMetagenomics

Identifiers

PMID38472519

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.