Evidence map›Paper›PMID 38472401›Full record

SynthesisLung2024

Pressure Support Ventilation Versus T-piece as Spontaneous Breathing Trials for Extubation of Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Luiza Mendes Fonseca, Pedro Matos da Câmara, Iane Miguel Pereira Lettieri, Caroline Serafim Dagostin, Arthur Oswaldo de Abreu Vianna

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Lung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luiza Mendes FonsecaDepartment of Medicine, Faculty of Medical Sciences of Minas Gerais, Inconfidentes Street, Number 443, apartment, Belo Horizonte, Minas Gerais, 1102, Brazil. luizamf1998@gmail.com.ORCID 0009-0001-4928-6121
Pedro Matos da CâmaraDepartment of Medicine, Federal University of Rio Grande Do Norte, Natal, Rio Grande Do Norte, Brazil.ORCID 0000-0003-1123-2651
Iane Miguel Pereira LettieriNo Filiation, Rio de Janeiro, Brazil.ORCID 0000-0002-7427-6179
Caroline Serafim DagostinDepartment of Medicine, University of the Extreme South of Santa Catarina, Criciúma, Santa Catarina, Brazil.ORCID 0000-0002-5047-4023
Arthur Oswaldo de Abreu ViannaProfessor of Medicine, Department of Medicine, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWeaning patients with COPD from mechanical ventilation (MV) presents a challenge, as literature on this topic is limited. This study compares PSV and T-piece during spontaneous breathing trials (SBT) in this specific population.

methodsA search of PubMed, EMBASE, and Cochrane in September 2023 yielded four randomized controlled trials (RCTs) encompassing 560 patients. Among these, 287 (51%) used T-piece during SBTs.

resultsThe PSV group demonstrated a significant improvement in the successful extubation rate compared to the T-piece (risk ratio [RR] 1.14; 95% confidence interval [CI] 1.03-1.26; p = 0.02). Otherwise, there was no statistically significant difference in the reintubation (RR 1.07; 95% CI 0.79-1.45; p = 0.67) or the ICU mortality rates (RR 0.99; 95% CI 0.63-1.55; p = 0.95).

conclusionAlthough PSV in SBTs exhibits superior extubation success, consistent weaning protocols warrant further exploration through additional studies.

Indexed as

Airway ExtubationPulmonary Disease, Chronic ObstructiveRandomized Controlled Trials as TopicVentilator WeaningHumansPositive-Pressure RespirationRespiration, ArtificialChronic obstructive Pulmonary diseaseExtubationMechanical ventilationMeta-analysisRandomized controlled trialsVentilator weaning

Identifiers

PMID38472401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.