ReviewAngewandte Chemie (International ed. in English)2024
Metalloradical Catalysis: General Approach for Controlling Reactivity and Selectivity of Homolytic Radical Reactions.
Review in Angewandte Chemie (International ed. in English), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Origin of Scission Selectivity for Phosphoranyl Radicals in Photoredox Catalysis.Journal of the American Chemical Society · 2026Article
- Cobalt-Catalyzed Radical Ligand Transfer (RLT) Enables Remote-Markovnikov Hydroamination of Alkenes.Angewandte Chemie (International ed. in English) · 2026Article
- Iron-Catalyzed Cyclopropanation of Allenes Using Unactivated Alkyl Sulfonium Salts.Angewandte Chemie (International ed. in English) · 2026Article
- Metalloradical Activation of Iodonium Ylides for Catalytic Radical Cyclization via Fe(III)-Based Metalloradical Catalysis.JACS Au · 2026Article
- Identification of an air- and moisture-tolerant MOF-based C-H amination catalyst.Chemical communications (Cambridge, England) · 2026Article
- Isolation and reactivity of an alkyl-substituted germanium(I) radical anion.Nature communications · 2026Article
- Photoactive Iminobismuthanes for Catalytic C-H Amination.Journal of the American Chemical Society · 2026Article
- Highly stereoselective synthesis of allylic β-lactamsChemical science · 2026Article
- Enantioselective C-H functionalization: logic and applications in the total synthesis of natural products.Chemical science · 2026Review
- Asymmetric Hydrogen Atom Transfer.ACS catalysis · 2026Review
- Enantioselective Intramolecular C-H Alkylation Catalyzed by a Nonsymmetric Chiral Cobalt Porphyrin.Journal of the American Chemical Society · 2026Article
- Controlled magnetic bistability of a helical non-Kekulé hydrocarbon on a Au(111) surface.Nature communications · 2026Article
- Three-component synthesis of β-thio tertiary alkylamines from simple alkenes via SScience advances · 2026Article
- Molecular Origins of Simultaneous Chemo-, Enantio-, and Substrate Selectivity in Non-Natural Photoenzymatic Radical Reactions.Journal of the American Chemical Society · 2025Article
- Enantioselective Radical Dearomative Conjugate Amination Enabled by Co(II)-Based Metalloradical Catalysis.Nature catalysis · 2025Article
- Cyano group translocation to alkenyl C(spNature communications · 2025Article
- Non-Innocent Ligands as Mediators for Visible-Light-Initiated Element-Carbon Bond Homolysis in Main Group Chemistry.Angewandte Chemie (International ed. in English) · 2025Review
- Asymmetric C-H Amination via Fe(III)-Metalloradical Catalysis Featuring α-Fe(IV)-Aminyl Radicals as Key Intermediates.Journal of the American Chemical Society · 2025Article
- Radical Sorting Catalysis via Bimolecular Homolytic Substitution (SJournal of the American Chemical Society · 2025Review
- Cu(I)-catalysed chemo-, regio-, and stereoselective radical 1,2-carboalkynylation with two different terminal alkynes.Nature communications · 2025Article
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Abstract
Since Friedrich Wöhler's groundbreaking synthesis of urea in 1828, organic synthesis over the past two centuries has predominantly relied on the exploration and utilization of chemical reactions rooted in two-electron heterolytic ionic chemistry. While one-electron homolytic radical chemistry is both rich in fundamental reactivities and attractive with practical advantages, the synthetic application of radical reactions has been long hampered by the formidable challenges associated with the control over reactivity and selectivity of high-energy radical intermediates. To fully harness the untapped potential of radical chemistry for organic synthesis, there is a pressing need to formulate radically different concepts and broadly applicable strategies to address these outstanding issues. In pursuit of this objective, researchers have been actively developing metalloradical catalysis (MRC) as a comprehensive framework to guide the design of general approaches for controlling over reactivity and stereoselectivity of homolytic radical reactions. Essentially, MRC exploits the metal-centered radicals present in open-shell metal complexes as one-electron catalysts for homolytic activation of substrates to generate metal-entangled organic radicals as the key intermediates to govern the reaction pathway and stereochemical course of subsequent catalytic radical processes. Different from the conventional two-electron catalysis by transition metal complexes, MRC operates through one-electron chemistry utilizing stepwise radical mechanisms.
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