Evidence map›Paper›PMID 38472096›Full record

ArticleACS applied materials & interfaces2024

Solid-Phase Extraction and Enhanced Amplification-Free Detection of Pathogens Integrated by Multifunctional CRISPR-Cas12a.

Zimu Tian, He Yan, Yong Zeng

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Zimu TianDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
He YanDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.ORCID 0000-0001-8389-5281
Yong ZengDepartment of Chemistry, University of Florida, Gainesville, Florida 32611, United States.ORCID 0000-0003-0537-109X
University of Florida · USUniversity of Florida Health · US

Funding

Extracellular Vesicle Proteomic Fingerprinting of Ovarian Cancer for Early Detection with a Nanoengineered MicrosystemR01CA260132 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI GODWIN, ANDREW K., ZENG, YONG · 2021 to 2025
$3.4M
Nano-Engineered Lab-on-a-Chip for Assessing HuR-Regulated Exosomes for Cancer Monitoring and Targeted TherapyR01CA243445 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI DIXON, DAN ALAN, XU, LIANG · 2019 to 2023
$3.0M
Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancerR33CA214333 · NCI · UNIVERSITY OF KANSAS LAWRENCE · PI GODWIN, ANDREW K., ZENG, YONG · 2017 to 2019
$1.2M
Integrative Functional Profiling of Tumor-Derived Extracellular VesiclesR33CA252158 · NCI · UNIVERSITY OF FLORIDA · PI XU, LIANG, ZENG, YONG · 2021 to 2024
$1.0M
NCI NIH HHS R01 CA243445NCI NIH HHS R01 CA260132NCI NIH HHS R33 CA214333NCI NIH HHS R33 CA252158
6 · The paper itself

Abstract

Public healthcare demands effective and pragmatic diagnostic tools to address the escalating challenges in infection management in resource-limited areas. Recent advances in clustered regularly interspaced short palindromic repeat (CRISPR)-based biosensing promise the development of next-generation tools for disease diagnostics, including point-of-care (POC) testing for infectious diseases. The currently prevailing strategy of developing CRISPR/Cas-based diagnostics exploits only the target identification and

Indexed as

Biosensing TechniquesNucleic AcidsBiological AssayCRISPR-Cas SystemsHuman papillomavirus 16Solid Phase ExtractionNucleic AcidsCRISPR/Cas12adetectionHPVmagnetic beadsPOCT

Identifiers

PMID38472096
PMCPMC13657438
OpenAlexW4392763687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.