ArticleJournal of the American Heart Association2024
Recurrence After Atrial Fibrillation Ablation and Investigational Biomarkers of Cardiac Remodeling.
Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Cryoballoon versus radiofrequency ablation for persistent atrial fibrillation: an updated systematic review and meta‑analysis.European journal of medical research · 2025Pooled it
- Pooled it
- Predictive Effect of GDF-15 on Adverse Outcomes After Cardiovascular Interventions: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2025Pooled it
- Conventional and Emerging Biomarkers for Predicting Post-Ablation Atrial Fibrillation Recurrence: An Updated Systematic Review.Cardiology research · 2026Review
- Circulating microRNAs in Atrial Fibrillation: Clinical Significance and Future Perspectives.Medicina (Kaunas, Lithuania) · 2026Review
- Association of cardiovascular-kidney-metabolic burden with recurrence after first ablation in patients with persistent atrial fibrillation.BMC cardiovascular disorders · 2026Article
- Analysis of risk factors for early recurrence after radiofrequency ablation in patients with atrial fibrillation and construction of a nomogram predictive model.Frontiers in cardiovascular medicine · 2026Article
- Development and Validation of an Explainable Machine Learning Model for Predicting Repeat Catheter Ablation for Atrial Fibrillation: A Single-Center Retrospective Cohort Study.International journal of general medicine · 2026Article
- Novel predictors of late recurrence after catheter ablation for atrial fibrillation: from biomarkers to artificial intelligence models.Frontiers in cardiovascular medicine · 2026Review
- Radiomic features of peri-left atrial epicardial adipose tissue and atrial fibrillation recurrence after ablation.Open heart · 2025Article
- Clinical Utility of the 4S-AF Scheme in Predicting Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation.Reviews in cardiovascular medicine · 2025Article
- Clinical, Electrocardiographic and Echocardiographic Predictors of Atrial Fibrillation Recurrence After Pulmonary Vein Isolation.Journal of clinical medicine · 2025Review
- Predictive value of echocardiographic parameter of diastolic dysfunction (Ea/Aa) combined with electrocardiographic P-wave dispersion for the detection of early recurrence of atrial fibrillation after radiofrequency catheter ablation.Frontiers in cardiovascular medicine · 2025Article
- The HALP Index Is Associated with the Recurrence of Persistent Atrial Fibrillation Following Radiofrequency Catheter Ablation.Journal of inflammation research · 2025Article
- Predicting Early recurrence of atrial fibrilation post-catheter ablation using machine learning techniques.BMC cardiovascular disorders · 2024Article
Corrections and comments
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Authors and funding
25 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundRecurrence after atrial fibrillation (AF) ablation remains common. We evaluated the association between recurrence and levels of biomarkers of cardiac remodeling, and their ability to improve recurrence prediction when added to a clinical prediction model. METHODS AND
resultsBlood samples collected before de novo catheter ablation were analyzed. Levels of bone morphogenetic protein-10, angiopoietin-2, fibroblast growth factor-23, insulin-like growth factor-binding protein-7, myosin-binding protein C3, growth differentiation factor-15, interleukin-6, N-terminal pro-brain natriuretic peptide, and high-sensitivity troponin T were measured. Recurrence was defined as ≥30 seconds of an atrial arrhythmia 3 to 12 months postablation. Multivariable logistic regression was performed using biomarker levels along with clinical covariates: APPLE score (Age >65 years, Persistent AF, imPaired eGFR [<60 ml/min/1.73m
conclusionsHigher angiopoietin-2 and interleukin-6 levels were associated with recurrence after atrial fibrillation ablation in multivariable modeling. However, the addition of biomarkers to a clinical prediction model did not significantly improve recurrence prediction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.