Evidence map›Paper›PMID 38471546›Full record

ArticleProceedings. Biological sciences2024

Building pyramids against the evolutionary emergence of pathogens.

Sylvain Gandon, Martin Guillemet, François Gatchitch, Antoine Nicot, Ariane C Renaud, Denise M Tremblay, Sylvain Moineau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings. Biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sylvain GandonCEFE, Univ Montpellier, CNRS, EPHE, IRD, Montpellier, France.ORCID 0000-0003-2624-7856
Martin GuillemetCEFE, Univ Montpellier, CNRS, EPHE, IRD, Montpellier, France.
François GatchitchCEFE, Univ Montpellier, CNRS, EPHE, IRD, Montpellier, France.
Antoine NicotCEFE, Univ Montpellier, CNRS, EPHE, IRD, Montpellier, France.
Ariane C RenaudDépartement de biochimie, de microbiologie et de bio-informatique, Faculté des sciences et de génie, Université Laval, Quebec city, Canada G1V0A6.
Denise M TremblayFélix d'Hérelle Reference Center for Bacterial Viruses, Université Laval, Québec City, Canada G1V 0A6.ORCID 0009-0008-7544-1739
Sylvain MoineauDépartement de biochimie, de microbiologie et de bio-informatique, Faculté des sciences et de génie, Université Laval, Quebec city, Canada G1V0A6.ORCID 0000-0002-2832-5101

Funding

Agence Nationale de la Recherche ANRNatural Sciences and Engineering Research Council of Canada
6 · The paper itself

Abstract

Mutations allowing pathogens to escape host immunity promote the spread of infectious diseases in heterogeneous host populations and can lead to major epidemics. Understanding the conditions that slow down this evolution is key for the development of durable control strategies against pathogens. Here, we use theory and experiments to compare the efficacy of three strategies for the deployment of resistance: (i) a

Indexed as

BacteriophagesCommunicable DiseasesBacteriaCRISPR-Cas SystemsHumansMutationbacteriophageCRISPR resistancedemographic stochasticityepidemiologyevolutionary emergenceinfectious disease control

Identifiers

PMID38471546
PMCPMC10932699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.