Evidence map›Paper›PMID 38471476›Full record

ArticleHormone research in paediatrics2025

Health-Related Quality of Life of Young Adult Women with a History of Premature Adrenarche.

Jussi Tennilä, Harri Sintonen, Pauliina Utriainen, Raimo Voutilainen, Jarmo Jääskeläinen, Jani Liimatta

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hormone research in paediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jussi TenniläKuopio Pediatric Research Unit, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Harri SintonenDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Pauliina UtriainenResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Raimo VoutilainenKuopio Pediatric Research Unit, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Jarmo JääskeläinenKuopio Pediatric Research Unit, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Jani LiimattaKuopio Pediatric Research Unit, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Kuopio University Hospital · FIUniversity of Eastern Finland · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChildren with premature adrenarche (PA) have increased adrenal androgen concentrations and earlier pubertal development than their peers. Early sexual maturation and exposure to androgens have both been associated with an increased risk for neuropsychological adversities in adulthood. Such adversities would presumably influence the experienced health-related quality of life (HRQoL) of those affected.

methodsIn a longitudinal case-control cohort study, 30 PA girls and 40 age-matched controls were followed from childhood to young adult age. The main outcome measure was the total 15D HRQoL score. In addition, we assessed specific dimensions of the questionnaire, the subjects' relationship statuses, and living arrangements.

resultsThere were no differences between the groups in the overall 15D scores (PA, 0.956 [0.052]; control, 0.947 [0.055]; p 0.482) or on any dimension of this instrument.

conclusionThe study suggests that a history of PA does not lead to impaired HRQoL in adult age.

Indexed as

AdrenarchePuberty, PrecociousQuality of LifeAdolescentAdultCase-Control StudiesChildFemaleHumansLongitudinal StudiesSurveys and QuestionnairesYoung AdultHealth-related quality of lifePremature adrenarche

Identifiers

PMID38471476
PMCPMC12133110
OpenAlexW4394594434

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.