Evidence map›Paper›PMID 38471232›Full record

ArticlePoultry science2024

Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers.

Hesam Shahininejad, Shaban Rahimi, Mohammad Amir Karimi Torshizi, Fatemeh Arabkhazaeli, Mahdi Ayyari, Alireza Behnamifar, Morteza Abuali, Jesse Grimes

Open access · goldAbstract readComparative Study
In one paragraph

Article in Poultry science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hesam ShahininejadDepartment of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 Iran.
Shaban RahimiDepartment of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 Iran.
Mohammad Amir Karimi TorshiziDepartment of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 Iran.
Fatemeh ArabkhazaeliDepartment of Parasitology, Faculty of Veterinary Medicine, University of Tehran, 14199-63114 Iran.
Mahdi AyyariDepartment of Horticultural Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 Iran.
Alireza BehnamifarDepartment of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 Iran.
Morteza AbualiDepartment of Pharmacognosy, Institute of Medicinal Plants-ACECR, Karaj, Alborz, 1419815477 Iran.
Jesse GrimesPrestage Department of Poultry Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, NC 27695-7608 USA. Electronic address: jgrimes@ncsu.edu.
Tarbiat Modares University · IRAcademic Center for Education, Culture and Research · IRNorth Carolina State University · USUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared 2 herbal anticoccidiosis drugs (water-soluble and feed-additive drugs) with monensin coccidiostat, toltrazuril (TTZ, anticoccidiosis drug), and Livacox Q (anticoccidiosis vaccine) in terms of their effects on the prevention and treatment of coccidiosis in broilers. In this study, 280 Ross 308 broiler chickens (a mix of both genders) were used in a completely randomized design with 7 treatments and 5 replications each including 8 chickens per replicate. On d 21 of rearing, all experimental groups, except for the negative control group (NC), were challenged with a mixed suspension of common strains of Eimeria, and the intended indices were assessed, including performance indices, number of oocysts per gram (OPG) of feces, intestinal injuries, and the total number of intestinal bacteria. In addition, the NC and the group receiving the monensin had greater body weight gain (BWG) (P < 0.05). At the end of week 6, the monensin group had the highest feed intake (FI), while the water soluble medicine treatment resulted in the lowest feed intake (P < 0.05). Regarding the lesion scores on day 28, the highest and lowest rates of jejunal injuries were observed in the positive control group (PC), the monensin and vaccine group respectively. The rate of oocysts excretion (oocysts per gram of feces = OPG) on different days was higher in the PC group, and the use of monensin could further reduce excretion compared to the other groups (P > 0.05). Based on a comparison of the population of lactic acid bacteria between the NC and both medicinal plant treated groups, the use of these products could increase the population of these types of bacteria. Moreover, the population of Escherichia coli was less considerable in the NC and herbal powder groups (P < 0.05). Overall, similar to commercial medicines, the herbal medicines used in this project can be effective in the prevention and treatment of coccidiosis and can improve profitability in broiler rearing centers by improving intestinal health.

Indexed as

Animal FeedChickensCoccidiosisCoccidiostatsDietEimeriaPoultry DiseasesProtozoan VaccinesTriazinesAnimalsDietary SupplementsFemaleMaleRandom AllocationCoccidiostatsProtozoan VaccinestoltrazurilTriazinescoccidiosislesion scoresmonensinoocyst excretionvaccine

Identifiers

PMID38471232
PMCPMC11067760
OpenAlexW4392203594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.