ArticlePloS one2024
The relationship between caregiver contribution to self-care and patient quality of life in heart failure: A longitudinal mediation analysis.
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02894502 (MOTIVATional intErviewing to Improve Self-care in Heart Failure Patients), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MOTIVATional intErviewing to Improve Self-care in Heart Failure Patients (MOTIVATE-HF): Study Protocol of a Three-arm Multicenter Randomized Controlled Trial
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Quality of Life in Chronic Heart Failure With Obstructive Sleep Apnea: A Systematic Review.Nursing open · 2025Pooled it
- Psychometric Properties of Caregiver Contribution and Self-Efficacy Scales in Cancer.Nursing & health sciences · 2026Article
- Feasibility of a Mobile-Based Home Monitoring System for Patients With Heart Failure: Mixed Methods Pilot Study.JMIR human factors · 2026Article
- Caregiver contribution to patient self‑care and quality of life among informal carers of adult patients with inflammatory bowel disease: a cross‑sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- The Impact of Informal Caregiving on Patient-Reported Outcomes, Psychological Well-Being and Quality of Life in Inflammatory Bowel Disease: A Systematic Review.Nursing reports (Pavia, Italy) · 2026Review
- Dual trajectories of capacity management behavior and quality of life in hemodialysis patients: a longitudinal study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Translation, cross-cultural adaptation, and psychometric validation of the Chinese version of the Caregiver Contribution to Self-Care of Coronary Heart Disease Inventory.Frontiers in public health · 2026Article
- Correlations Between Coronary Artery Calcium Scores and Vitamin A, the Triglyceride/High-Density Lipoprotein Ratio, and Glycated Hemoglobin in At-Risk Individuals in Saudi Arabia: A Comprehensive Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Interdependence of health between patients with colorectal cancer and family caregivers: a cross-sectional study.BMC nursing · 2025Article
- Factors associated with dementia risk reduction lifestyle in mild cognitive impairment: a cross-sectional study of individuals and their family caregivers.BMC neurology · 2025Article
- Psychometric Testing of the Kansas City Cardiomyopathy Questionnaire 12 in A European Population.The Journal of cardiovascular nursing · 2025Article
- Examining the clinical role and educational preparation of heart failure nurses across Europe. A survey of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) and the Association of Cardiovascular Nursing and Allied Professions (ACNAP) of the ESC.European journal of heart failure · 2025Article
- Artificial intelligence in personalized rehabilitation: current applications and a SWOT analysis.Frontiers in digital health · 2025Review
- Language Validation and Cultural Adaptation of the Italian Version of the Family Caregiver Quality of Life Scale.Nursing reports (Pavia, Italy) · 2024Article
- Association Between Family Caregiver Oral Care Practices and Oral Health Status in Rehabilitation Ward Patients With Dysphagia.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with heart failure may experience poor quality of life due to a variety of physical and psychological symptoms. Quality of life can improve if patients adhere to consistent self-care behaviors. Patient outcomes (i.e., quality of life) are thought to improve as a result of caregiver contribution to self-care. However, uncertainty exists on whether these outcomes improve as a direct result of caregiver contribution to self-care or whether this improvement occurs indirectly through the improvement of patient heart failure self-care behaviors.
aimsTo investigate the influence of caregiver contribution to self-care on quality of life of heart failure people and explore whether patient self-care behaviors mediate such a relationship.
methodsThis is a secondary analysis of the MOTIVATE-HF randomized controlled trial (Clinicaltrials.gov registration number: NCT02894502). Data were collected at baseline and 3 months. An autoregressive longitudinal path analysis model was conducted to test our hypotheses.
resultsWe enrolled a sample of 510 caregivers [mean age = 54 (±15.44), 24% males)] and 510 patients [mean age = 72.4 (±12.28), 58% males)]. Patient self-care had a significant and direct effect on quality of life at three months (β = 0.20, p < .01). Caregiver contribution to self-care showed a significant direct effect on patient self-care (β = 0.32, p < .01), and an indirect effect on patient quality of life through the mediation of patient self-care (β = 0.07, p < .001).
conclusionPatient quality of life is influenced by self-care both directly and indirectly, through the mediation of caregiver contribution to self-care. These findings improve our understanding on how caregiver contribution to self-care improves patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.