Evidence map›Paper›PMID 38470771›Full record

ArticleNanomaterials (Basel, Switzerland)2024

The Effect of Stereocomplexation and Crystallinity on the Degradation of Polylactide Nanoparticles.

Chuan Yin, Jenny Hemstedt, Karl Scheuer, Maja Struczyńska, Christine Weber, Ulrich S Schubert, Jörg Bossert, Klaus D Jandt

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chuan YinChair of Material Science (CMS), Otto Schott Institute for Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena, Germany.
Jenny HemstedtChair of Material Science (CMS), Otto Schott Institute for Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena, Germany.
Karl ScheuerChair of Material Science (CMS), Otto Schott Institute for Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena, Germany.
Maja StruczyńskaChair of Material Science (CMS), Otto Schott Institute for Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena, Germany.
Christine WeberInstitute of Organic Chemistry and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany.ORCID 0000-0003-0712-5255
Ulrich S SchubertInstitute of Organic Chemistry and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany.
Jörg BossertChair of Material Science (CMS), Otto Schott Institute for Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena, Germany.
Klaus D JandtChair of Material Science (CMS), Otto Schott Institute for Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743 Jena, Germany.
Schott (Germany) · DEFriedrich Schiller University Jena · DE

Funding

Deutsche Forschungsgemeinschaft project number 316213987 - SFB 1278 (project A06).
6 · The paper itself

Abstract

Polymeric nanoparticles (PNPs) are frequently researched and used in drug delivery. The degradation of PNPs is highly dependent on various properties, such as polymer chemical structure, size, crystallinity, and melting temperature. Hence, a precise understanding of PNP degradation behavior is essential for optimizing the system. This study focused on enzymatic hydrolysis as a degradation mechanism by investigation of the degradation of PNP with various crystallinities. The aliphatic polyester polylactide ([C

Indexed as

degradationdrug deliverynanostiffnesspoly d-lactidepoly l-lactidepolymer nanoparticlesstereocomplex

Identifiers

PMID38470771
PMCPMC10934930
OpenAlexW4392238806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.